我院心外科Ⅰ类切口手术围手术期抗菌药物的应用调查.pdfVIP

中国药物应用与监测 2013 年12月第10卷第6 期 Chinese Journal of Drug Application and Monitoring, Vol.10, No.6, December 2013 我院心外科Ⅰ类切口手术围手术期抗菌药物的应用调查 方京毅，魏建英，袁丽萍（清华大学第一附属医院药学部，北京100016 ） [摘要]　目的：调查我院心外科I 类切口手术围手术期抗菌药物的应用情况，为临床合理用药提供参考。方法：随机抽取 我院2012 年1 – 6 月100例心脏手术I 类切口围手术期使用抗菌药物的病历，并对数据进行统计分析。结果：100份病历中， 抗菌药物初次给药时机选择不合理的8 例，术后使用抗菌药物疗程不合理的16例，抗菌药物品种选择不合理的14例。联 合用药共33 例，细菌培养送检2 例，抗菌药物的联合应用较好。抗菌药物初次给药时间在术前0.5 ~ 2 h 的病历占76% ，手 术时长 3 h 或失血 1500 mL 的病历术中追加抗菌药物的比例为9% ，用药时长 72 h 的病历占71% ，用药品种选择基本合 理。结论：我院心外科I 类切口手术围手术期抗菌药物的使用基本合理，将进一步加强对抗菌药物的监督管理，促进其在临 床的合理使用。 [关键词]　心脏外科手术；围手术期；抗菌药物；合理用药 [ 中图分类号]　R969.3 [ 文献标识码]　A　 [ 文章编号]　1672 – 8157(2013)06 – 0349 – 03 Investigation analysis of antibacterials used in type Ⅰincision of cardiac operations during perioperative period in our hospital FANG Jing-yi, WEI Jian-ying, YUAN Li-ping(Department of Pharmacy, the First Hospital of Qing-hua University, Beijing 100016, China) [ABSTRACT]　Objective: To explore the application of antibacterials in cardiac surgical procedures during perioperative period in our hospital, and provide the reference for rational drug use. Methods: A total of 100 cases undergoing open-heart surgery with type incision from January 2012 to June 2012 were randomly selected and statistically analyzed. Among the 100 cases, Ⅰ Results ： there were 8 cases with irrational administration time, 16 cases with irrational duration in postoperative use of antibacterials and 14 cases with unsuitable categories of antibacterials drugs. There were 33 cases with drugs combination and 2 cases with bacterial culture. The rate of cases administrated antibacterials within 0.5 – 2 h before operation was 76%. The rate of appended antibacterials during operation in the cases with operation time more than 3 h or blood loss more than 1500 mL was 9%. The rate of the cases with administrati