慢性肾功能不全患者合理应用抗菌药物情况分析.pdfVIP

慢性肾功能不全患者合理应用抗菌药物情况分析 李平’，李方剑，刘永刚(武警广东总队医院药剂科，广州510507) 中图分类号R978．1 文献标志码B 文章编号1672—2124(2012)05—0425-03 摘要 目的：了解武警广东总队医院慢性肾功能不全惑者抗茵药物临床应用情况，为提高抗茸药物合理应用水平提供理论依据。 要剂量调整的为86例，已调整的占需调整的37．2％(32／86)；肌酐清除率(Cer)10rr·min。组调整率最高．为51．7％。结论：大 部分医生具备慢·】生肾功能不全患者应用抗菌药物应根据患者肾功能情况进行剂量调整的意识，但需加强宣传学习抗茵药物知识。 关键词慢性肾功能不全；抗茵药物；用药调整；病例调查；分析 inAntibioticUseinPatientswith Renal Rationality ChronicInsufficiency LI of General of Ping’，LIFang-jian，LIUYong—gang(DepLPharmacy，GuangdongHospitalPeople’s Armed 51 Polices，Guangzhou0507，China) ABSTl己ACT intotheclinicaluseofantibioticsin withchronicrenal in OBJECTIVE：To probe patients inst曲eieney General of ArmedPolicesso矗sfo theoreticbasisfor clinicalrational GuangdongHospitalPeople’S provide improving antibioticusein withchronicrenal inour from 2009 dmguse．METHODS：The patients f打s“fficieneyhospitalJanuary toDecember2010were tlletotal139cases dosesfor86awaited fe*tewed，the analyzedretrospectively．RESULlS：In thedosesin been whom，tlle whosecreatinineclearance adjusting，and only37．2％(32／86)haveadjusted，of patients mL·rain“tookthelcadwith ofthe ha,ethe rate(Ccr)was10 51．7％．CONCLUSION：M08t knowledge physicians tllatthe for dosesofantibioties withchronicrenal shouldbe basedon patients insufficieneyadjusted funotion：however．theand aboutthe ofantibioticsremainstobeintensified． propagandalearning knowledge KEY W0砌)sChronicleual insumciency