检索附件：EI收录文情况.docVIP

检索附件：EI收录论文情况 Accession number: 20104813442918 Title: Au@Pt nanostructures as oxidase and peroxidase mimetics for use in immunoassays Authors: He, Weiwei1, 3 ; Liu, Ying2 ; Yuan, Jinshan2 ; Yin, Jun-Jie4 ; Wu, Xiaochun1 ; Hu, Xiaona1 ; Zhang, Ke1 ; Liu, Jianbo1 ; Chen, Chunying2 ; Ji, Yinglu1 ; Guo, Yuting1 Author affiliation: 1 CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, Beijing 100190, China 2 CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China 3 Institute of Surface Micro and Nano Materials, Xuchang University, Xuchang 461000, China 4 Center for Food Safety and Applied Nutrition, Food and Drug Administration, College Park, MD 20740, United States Corresponding author: Yin, J.-J. (JunJie.Yin@) Source title: Biomaterials Abbreviated source title: Biomaterials Volume: 32 Issue: 4 Issue date: February 2011 Publication year: 2011 Pages: 1139-1147 Language: English ISSN: CODEN: BIMADU Document type: Journal article (JA) Publisher: Elsevier Ltd, Langford Lane, Kidlington, Oxford, OX5 1GB, United Kingdom Abstract: In this paper, we demonstrated that Au nanorods coated with a shell composed of Pt nanodots (Au@Pt nanostructures) exhibited intrinsic oxidase-like, peroxidase-like and catalase-like activity, catalyzing oxygen and hydrogen peroxide reduction and the dismutation decomposition of hydrogen peroxide to produce oxygen. Based on these findings, we established an Au@Pt nanostructures based enzyme linked immunosorbent assay (ELISA) for the detection of mouse interleukin 2 (IL-2). In comparison with natural enzymes, Au@Pt nanostructures have advantages of low cost, easy preparation, better stability, and tunable catalytic activity (compared with HRP), which make them a promising enzyme mimetic candidate and may find potential applications in biocatalysis, bioassays, and