淋巴细胞性垂体炎和肉芽肿性垂体炎的诊断和治疗_杨义.pdfVIP

668 2005 11 21 11 Ch in J N eurosurg, N ovem ber 2005, Vol 21, No11 杨义 苏长保 杨堤 任祖渊 王任直 7 2 282, 55 MR I, , 6, 3 1- 6 , , , , , , ; ; D iagnosis andm anagement of lymphocytic and granulom atous hypophysitis YANG Yi, SU Changbao, YANG Ti, et al. Departm ent of N eurosurgery, P eking Union M e ical College H osp ital, B eij ing 100730, China Abstract Objective T o discuss the d iagnosis and m anagem ent of L mphoc tic and granulom atous h poph sitis. M ethods In th is retrospective stud , w e review ed the clin ic data, endocrinological and rad iological ex am ation, operative find ing and effectw ith 7 cases of l m phoc tic h poph sitis and 2 cases of granu lom atous h poph sitis. The m ean age w as 282 ears old, and mean histor w as 55 m onths. The clin ical signs were headache, d iabetes inspidus, h pop itu itarism, visual defect b turns. M agnetic resonance mi aging (MRI) revealed sellar lesion w ith hom o- or h poindense at T 1 and pitu itar stalk enlargem en t. R esults Transsphenoidal surger w ere perform ed on all the patients. T otal rem ovalw ere ach ievel in 6 cases and partial rem oval in 3 caes. Follow - up w ere 1- 6 ears, m ost of patien ts had rem ission of headache, d iabetes insp idus, and visual defect, but on l som e patients had mi provem ent in h pop itu itarism. Conclusions It w as d ifficu lt to m ake correct d iagnosis of l mphoc tic and granulom atous h poph sitis. T ranssphenoidal surger should be performed to patients w ith clin ical signs at once and lesion shou ld be removed totall to increase the operation effect. Key words Pitu itar h poph sitis; D iagnosis; M anagem ent , 2; 6, 10000~ 13500m l 2; 19841 2001 10 2, 3; 7, 2, 4; 1 ,