咳嗽变异性哮喘的临床特征及其与典型哮喘的关系.pdfVIP

150 () 20116 5 3 Chin J Asthma (Electronic Edition) ,June 2011,Vol.5,No.3 席寅 赖克方 陈如冲 罗炜 陈桥丽 王法霞 林玲 许丹媛 杨业 ( CVA) , CVA 2002 12010 1 CVA , , / PEF 18 CVA ,8 , , CVA ( ) ; 91 CVA 74. 7 ,46.2 ;:63. 5 51.4 47.3 37.8 36.5 ; CVA 74.7 ( EOS) 2.5 58 4. 2(1~ 8.5) , 8 ( 8/ 58, 13.8 ) , CVA [12(20) vs 6(4) , P 0.05] ,8 1 12 , 50 CVA 33 12 , ( P 0. 05)CVA EOS EOS ( P 0.05) CVA ,, CVA ;; ; Cli nical char act eri st ics of cough variant ast hma and its relasi onship wit h the cl assic ast hma XI Yin, LAI Kef ang, CH EN R uchong, L UO Wei, CH EN Qiaoli, WA NG Fax ia, LIN L ing, X U any uan, YAN G Ye. State Key Laboratory of Resp iratroy isease ( Guangzhou Medical College), Guangzhou Institute of Resp iratory isease, the First Af f iliated H osp ital of Guangzhou Medical College, Guangzhou510120, China Corresp onding author :LAI Kef ang, Email: klai@ 163. com Abst ract Objective To study the clinical characteristics of adult cough variant asthma ( CVA) and investigate the proportion of CVA developed classic asthma, explore the risk factors for the development of asthma in patientswith CVA.Methods The clinical characteristics and basic examinations of 91 CVA patients were retrospectively assessed. Moderate dose budesonide or compounds of bronchodilator and corticosteroid were inhaled in all patients at least 8 weeks. According to whether the patients developed asthmatic symptoms of wheezing and dyspnea through the clinic or telephone follow up, they were divided into two groupsthe pure CVA group and the asthma group. The pulmonary function parameters, eosinophil proportion of induced sputum and peripheral blood,skin prick test positive rate and ICS usage of these two groups were compared. Result s The incidence of nocturnal or morning cough in 91 CVA patientswas 74.7 , the proportion of theseCVA patientswith allergic rhinitis hist