ADS系列大孔吸附树脂纯化山楂叶总黄酮工艺研究_董恒颖.pdf

T ianjin Pharmacy 2010 22 5 67 , , 28~ 30 2 g IPA- 750 2. 5 g ,, ,, 28 , 2 g IPA- 750 2. 3 g 7- AVCA , 5. 2 32: , , , IPA ,, , - 750 7- - 3- , 3% ,, 5. 3 pH 3 3: pH , , , , pH ,, , pH , , , pH , 7- - 3- 1 , , . 7- - 3- - 3- - 4- ., 1993, 24( 4): 246 7-AVCA, 2 K ameyama, utaka. Process for producing 3- alkenylcephem compound. pH 8. 0 JP, WO 9855485. 1998- 12- 10 5. 4 3 4: 3 , , . IPA - 750 , , 28 30 7-ADCA. , 2003. 33( 5): 37 * ADS , (, 300457) : ADS: , ADS: ADS- 8 ,: pH 4. 5, 1000mg/L, 3 BV /h, 100ml( 5 BV); 40%, 2 BV /h, 150 ml( 7. 5 BV), 80% : ADS - 8 ,, : R917 : A : 1006-5687( 2010) 05-0067-05 Purification process for flavonoids from hawthorn leaveswith ADS type ofmacroporous resin Dong Hengying, W ang ing ( T ianjinHulida Biotechnology co Ltd, T ianjin 300457) ABSTRACT Objective: To investigate the technicalparameters of purification process of total flavonoids from hawthorn leavesw ith ADS type ofmacroporous resin. M ethods: The conditions ofpurification of total flavonoids from hawthorn leaveswere screenedw ith adsorbing capacity and desorption rate of total flavonoids as indicators. Results: Among six types ofmacroporous adsorption resin choosed, ADS- 8 is the best resin for separating and purifying of flavonoids from hawthorn leaves. The optmi um conditions are: the concentratio