PET在胃癌诊断中的价值与CT对照研究改编前.docVIP

PET与CT在胃癌诊断中的价值对照 陈 凛1，卫 勃1，邵明哲2，田嘉禾2，姚树林2，尹大一2，孔庆龙1，唐建军1，李 荣1 （1．解放军总医院普外科，北京 100853；2．解放军总医院核医学科） [收稿日期] 2002-12-25 [修回日期]2003-7-15 [基金项目] 全军“十五”科研基金课题（01MA095） [作者简介] 陈凛，男，43，教授，硕士 [摘要] 目的： 评价PET和CT在胃癌诊断中的价值及优缺点。方法：28例胃癌患者术前行PET全身显像，23例行CT检查，将以上结果和病理分期对照。结果：PET和CT对胃癌局部病灶的显示率分别为96.4%和82.6％， PET对淋巴结的检测准确性（84.2％）高于CT（66.7％）。PET检测出8例远处转移患者，CT漏诊3例。结论： PET相对于CT能更准确检测原发和复发胃癌淋巴结及远处转移灶，对胃癌的临床诊断有较高的应用价值。 [关键词] 胃肿瘤；体层摄影术，发射型计算机；诊断 [中图分类号] [文献标识码] A Diagnostic value of positron emission tomography in gastric carcinoma correlation with computed tomography CHEN Lin， WEI Bo， SHAO Ming-zhe， TIAN Jia-he， YIN Da-yi， YAO Shu-lin， (Department of General Surgery， PLA General Hospital， Beijing 100853，china) [Abstract] Objective: A study was performed to evaluate the diagnostic value for positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) in patients with primary or recurrent gastric cancer correlated with computed tomography. Methods: 28 patients were included in the study. All patients had a PET scan. Preoperative staging of gastric cancer with CT were performed in 23 patients. These results were compared with the histopathological staging to evaluate the accuracy and usefulness of PET preoperation staging of patients with gastric cancer. Results: The accuracy in detecting primary tumor (T) by PET and CT was 96.4% and 82.6% respectively. For N the PET scan was accurate in 84.2% compared with CT in 66.7%. PET identified 8/8 patients with distant metastases and CT 4/7. Conclusion: PET scanning is a sensitive method for detecting lymph node and metastatic leision in patients with primary or recurrent gastric carcinoma compared with CT. PET appeared to be better in assessing recurrent tumour than CT. [Key words] Stomach neoplasm；Tomography，emission-computed；Diagnosis 胃癌诊断多以胃镜活检和影像学检查为主。近年来螺旋CT和PET(正电子发射型断层扫描成像 positron emission tomography)的迅速发展，使胃癌的诊断准确性显著提高。本文作者将螺旋CT扫描和PET成像结果与胃癌患者术后病理结果对照，以评价这两种方法在胃癌诊断中的价值及其优缺点。 1 对象和方法 1.1 对象 2001年7月