老年睡眠呼吸暂停综合征与糖尿病关系的流行病学调查.docVIP

老年睡眠呼吸暂停综合征与糖尿病关系的流行病学调查 作者：慈书平 张希龙 戴煌 杨春雷 胡仁学 作者单位：212001江苏省镇江市，解放军第三五九医院内科(慈书平，戴煌，杨春雷，胡仁学);210029江苏省南京市，南京医科大学第一附属医院呼吸内科(张希龙) 【摘要】 目的 调查老年人睡眠呼吸暂停综合征(SAS)与2型糖尿病(T2DM)的关系。 方法 对3286例老年人，采用家访式问卷调查，其中男1824人，女1462人，年龄60～92岁，平均(69 8)岁。随机抽样628人进行多导睡眠仪检查。 结果 3286例老年人群中SAS患者为959人(292%);糖尿病105例(32%)，其中SAS组84例(88%)，无SAS组为21例(09%)，2组比较差异显著(P 001)。Logistic多元回归分析SAS是T2DM的独立危险因素(P 001)。 结论 本调查资料提示，老年人SAS患病率为292%。SAS组T2DM的发生率显著高于无SAS组，两者呈显著正相关关系。 【关键词】 睡眠呼吸暂停综合征; 糖尿病; 流行病学调查; 老年人 Epidemiologic study on relationship between sleep apnea syndrome and diabetes in the elderly CI Shuping, DAI Huang, YANG Chunlei, HU Renxue. Department of Internal Medicine，the 359th Hospital of PLA, Zhenjiang 212001，China;ZHANG Xilong.Department of Respiratory Medicine，the First Affiliated Hospital，Nanjing Medical University，Nanjing 210029，China 【Abstract】 Objective To investigate the relationship between sleep apnea syndrome(SAS) and type 2 diabetes in the elderly. Methods The questionnaire investigation by home visiting were performed in 3286 elderly people (1824 male and 1462 female cases). The average age was 69 8 (range，60-92 years old) . 628 cases selected by cluster sampling randomly were examined with polysomography. Results In 3286 elderly people，959 cases(292%) were present with SAS and 105 cases(32%) were present with type 2 diabetes. There were 80 cases(88%) of type 2 diabetes in SAS group and 21 cases(09%) of type 2 diabetes in nonSAS group. There was significant difference in incidence of type 2 diabetes between the two groups(P 001). The logistic multivariate regression analysis showed that SAS was an independent high risk factor of type 2 diabetes. Conclusions According to the survey data, the morbidity of SAS in elderly people is 292%. The morbidity of type 2 diabetes in SAS group is much higher than that in nonSAS group, SAS shows positive correlation with type 2 diabetes. 【Key words】 sleep apnea syndrome; diabetes; epidemiologic study; elderly 睡眠呼吸暂停综合征(SAS)与2型糖尿病(T2DM)关系的流