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6 5 Vol. 6 No.5 2008 9 Chinese Journal of Pharmaceutics Sep. 2008 p.264 (2008 110016 RSD 33 80 50 % 4 cm PEG 4000PEG 60003:1 R 94 A Rhodiola crenulata 1977 [1] [2] [3-4 ] [5] 1 SZCL DT100 : 080317 : (1981), (), , , Tel. E-mail js102181@; (1957), (), , , , Tel.02423986258, E-mail li_sanming@ 5 265 PEG 4000PEG 6000 Rhodiola crenulata 2 2.1 PEG 4000PEG 60001.11.2 mg•L-1 PEG 4000 PEG 60001:02:1 3:10:1 151515 1 Table 1 Effects of matrix composition on the hardness, degree of sphericity, tailing and dissolution time of Rhodiola crenulata dropping pills Circularity degree/ m(PEG4000): m(PEG6000) Hardness /score Tailing/score tdissolution /min, x ±s score 1:0 3 2 1 6.32±0.19 2:1 4 4 5 6.58±0.23 3:1 5 5 5 6.18±0.24 0:1 3 2 1 6.84±0.18 PEG 4000PEG 6000 PEG 4000PEG 60003:1 3:1 2.2 PEG 4000 PEG 6000 3:11:51:31:2 3:5 15 15 15 2 Table 2 Effects of drug content on the hardness, degree of sphericity, tailing and dissolution time of Rhodiola crenulata dropping pills