冠心病患者血浆纤维蛋白原与小而密低密度脂蛋白的关系_秦勤.pdfVIP

# 584 # 2003 8 31 8 Chin J Cardi l, August 2003, V l. 31 N . 8 ## 秦勤 耿婕 崔让庄 毛用敏 寇璐 赵炳让 惠汝太 = ( Fib) ( sLDL) Clauss 234 164 Fib , sLDL , ( T C) ( T G) ( LDL-C) ( HDL-C) 12 3 , Fib sLDL Fib ( HDL-C ) , P 01 05, Fib sLDL ( P 0105) sLDL ( r = 01452, P 01 00 1) , Fib ( y = 4117x + 44167) sLDL , Fib sLDL , Fib = ; , LDL ; ; Relationship between fibrinogen and small low-density loipoprotein particles in coronary heart disease QIN Qin, GEN G Jie, C UI Rang-z huang , et al1 Tianj in Chest Hosp ital, Tianj in 3 51, China = Abstract Objective T investigate the relati nship between small l w-densit y lip pr tein ( sLDL) particles and fibrin gen in c r nary heart disease ( CHD) 1 Methods In a case-c ntr l study plasma lipids levels, small dense LDL percentage f t tal LDL and fibrin gen level were measured in 234 subjects with angi graphically d cumented CHD and 164 subjects with ut CHD ( ex cluded by c r nar graphy ) 1 Fibrin gen level was det ected by Clauss and sLDL level was detected by PAGE1 Acc rding angi graphy, patients w ere divided int single- , d uble- and triple- vessel gr ups1 W e expl red the relati nship between small, dense LDL level and fibrin gen in different gr ups1 Results The levels f T C, T G, LDL , small LDL and fibrin gen w ere significantly higher in patients with CHD than th se in c ntr ls ( small LDL : 581 70 ? 5125% vs 541 67 ? 61 03% , Fib: 31 30 ? 0179g/ L vs 21 82 ? 0172g/ L , P 0105) 1 The mean plasma HDL level was l wer in CHD patients than that in t he c ntr l gr up ( P 0105) 1 As the sten sis vessels increased, the sLDL and fibrin gen levels als increased ( P 01 05) 1 The fibrin gen levels f n sten sis, single- , d uble- and triple-vessel g