呼吸机相关性肺炎嗜麦芽寡养单胞菌感染的临床耐药分析.pdfVIP

　　 　 　 　 　　　　　　Medical Laboratory Science and Clinics ,2008 ,Vol 19 ,No . 1 　医学检验与临床 　2008 年第 19 卷第 1 期 ·12 · 呼吸机相关性肺炎嗜麦芽寡养单胞菌 感染的临床耐药分析 陈　梅 　利玉欢 　潘访谦 　杜燕娇 　陈振华 (南方医科大学附属南海人民医院 ,南海 528200) ( ) ( ) 【摘要】　目的　研究嗜麦芽寡养单胞菌 Stenotrophomonas maltophlia ,sm 在 ICU 病房呼吸机相关性肺炎 VAP 感染及耐药 情况 。方法 　回顾分析 2004 年 11 月～2006 年 3 月 ICU 病房机械通气患者发生 VAP 的临床资料 。结果 　嗜麦芽寡养单孢菌 为我院 ICU 病房 VAP 的主要病原菌占18. 2 %居感染病原菌首位 ;药敏结果显示 :嗜麦芽寡养单胞菌对亚胺培南天然耐药 ,并 对大多数抗菌药物耐药 ,仅对 SXT 、CIP 耐药率较低 ,分别为 20 % 、40 % 。结论 　嗜麦芽寡养单孢菌是我院 ICU 病房医院感染的 主要病原菌 ,对抗菌药物具多重耐药性 ,值得临床关注 。 【关键词】　呼吸机相关性肺炎 ;嗜麦芽寡养单孢菌 ;感染 ;抗生素 Clinicall analysis of drug resistence of stenotrophomonas maltophilia infection in ventilator - associated pneumo nia 　Chen Mei ,Li Yuhuan ,Pan Fangqian ,Du Yanj iao ,Chen Zhenhua 　People ’s Hospital of Nanhai ,Affilia ted Nanfang Medical university ,Foshan City , Guangdong 528200 ,China 【Abstract 】Objective To investigate the drug resistance of stenotrophomonas maltophilia ( sm) infection in ventilator - associated pneumo nia . Methods Data of patients in ICU who received ventilation and suffered ventilator - associated pneumonia from Nov ,2004 to March ,2006 were collected and analyzed. Results The infection rate of stenotrophomonas maltophilia was 18. 2 % and was the main pathogen of ventilator - associated pneumonia in ICU . Drug resistance results show that stenotrophomonas maltophilia was naturally resisted to lmipenem and most other antibiotics. Its resistance rate to SXT and CIP was relatively low ,separately 20 % and 40 %. Conclusions Stenotrophomonas maltophilia was the main pathogen of ICU hospital infection in our hospital and was multi - resisted to the antibiotics ,which should be noted in clinical practice . 【Key words】Ventilator -