慢性多发性抽动症的脑电图与临床研究.pdfVIP

·论著· 慢性多发性抽动症的脑电图与临床研究 石志鸿，张本恕，程 焱，黄恩强 [摘要]目的：探讨慢性多发性抽动症(抽动秽语综合征，TS)的脑电图特点及与临床的关系。 方法：对214例TS患者的脑电图与临床变量进行分析。结果：TS患者EEG异常率为62．6％，发病年 龄≤10岁的患者脑电图异常率为66．5％，高于发病年龄10岁的患者(42．9％)。病程中有秽语的患者 脑电图异常率(82．1％)明显高于无秽语的患者(59．7％)。性别、家族史、伴随性格行为问题对脑电图无 明显影响。结论：TS患者存在轻微脑功能障碍，发病年龄和秽语影响脑电活动的异常率。 [关键词]抽动秽语综合征(TS)；抽动症；脑电图；临床 The clinical on and Tourette electroencephalograminvestigation syndrome al SHI Benshu，CHENGYan，et Zhihong，ZHANG Institute Huanhu ofNeurology，Tia，巧inHospital，Tianjin，(300060)，China the of clinical investigaterelationship [Abstract]Objective：To electroencephalograms(EEGs)and characteristicsoftics(GillesdeIaTourette clinicalsourceof214TS syndrome，TS)．Methods：The pa— tientswassummarizedand total rateofEEGsofthe214TS abnormality analyzed．Results：The patients was ratewas onthe with of 62．6％．However，theabnormalityhigher patientsage onset≤10years thatinthe withofonset10 ratewas (66．5％)than patientsage years(42．9％)．Theabnormalityhigh- erinthe with thanthatinthe without patientscoprolalia patients coprolalia．Sex，familyhistory，character andbehavior havenoeffectOnEEGs．Conclusion：TheTS hasminimalbrain changes patients dysfunc— tion．Theofonsetandthe of influencethe rateofEEG． age symptomcoprolalia abnormality delaTourette characteristics [Keywords]Gilles syndrome(TS)；Tics；EEG；clinical 慢性多发性抽动症又称抽动秽语综合征(Gilles内科门诊及住院病人，其中男性172例，女性42例， delaTourette sydrome，TS)，是以突发的快速的及男女比例为4：l。诊断参照DSM一Ⅳ关于抽动障碍 反复的非节律