牙周治疗前后血清抗体滴度及亲和性的变化.pdfVIP

188 2000 5 35 3 Chin J S oma ol, May 2000, Vol 35, No 3 欧阳翔英 曹采方 陈智滨 ! ( Porphyromonas gingivalis, Pg ) , ELISA , 17 1 6 Pg381 IgG ( P 0001) , , ( P 00 1) ; , Pg38 1 , ∀ # ! ; ; ; ; Titer and avidity of serum antibody to Porp hy romonas g ingivalis before and after periodontal therapy OUYANG Xiangying, CAO Cafiang, CHEN Zhibin Department of Perio ontology, School of Stomatology, Beij ing Me ical University, Beij ing 100081, China Abstract! Obj ective To observe he changes of i er and avidi y of serum an ibody o Porp hyromonas gingivalis ( Pg) before and one mon h af er periodon al herapy , and o observe he correla ion of i er and avidi y of an i Pg IgG w i h clinical indices Methods ELISA and DEAELISA w ere used o de ermine he i er and avidi y of serum IgG an ibody o Pg381 before and one mon h af er periodon al rea men in 17 periodon i is pa ien s and 6 heal hy con rol subj ec s Results The i ers of an iPg IgG an ibody w ere higher in periodon i is pa ien s han in heal hy con rol subjec s ( P 0001) All pa ien s w ere seroposi ive ( i ers o Pg w ere higher han 2fold above he median for con rol subjec s) IgG an ibody avidi y o Pg in periodon i is pa ien s w ere no found o be significan ly lower han ha in con rol groupThe i ers o Pg decreased signif ican ly a one mon h af er periodon al herapy, bu an ibody avidi y didn changeSerum an i Pg an ibody i ers had a endency of nega ive correla ion w i h probing dep hThe an ibody i ers w ere signif ican higher in periodon i is pa ien s w i h ∃ 5 mm mean probing dep h han in pa ien s wi h 5 mm mean probing dep h Conclusions I is sugges ed ha he humoral immune response o Pg 381 is pro ec ive and his pro ec ive eff ec mainly depends on he i er of an ibody Key words! Periodon i is; Porphyromo