环境内分泌干扰物快速筛选方法研究进展.pdfVIP

综述文章（Reviews ） 环境内分泌干扰物快速筛选方法研究 进展 康亦珂，汝少国，王蔚 中国海洋大学海洋生命学院，山东青岛266003 摘要 为了减少和避免自然界中日益增多的环境内分泌干扰物对生物体及人类的危害，建立方便、有效、快捷的筛选方法，以从环境 污染物中检测出具有潜在的干扰内分泌系统的化学物质等已成为环境科学的热点研究方向。 本文从 个研究层面分类综述了近年 4 来环境内分泌干扰物快速筛选方法的研究进展，分析了各类筛选方法的优缺点，展望了其发展前景。 关键词 环境内分泌干扰物；快速筛选；生物筛选法 中图分类号 文献标识码 文章编号 （ ） X171.5 A 1000-7857 2010 12-0099-05 Progress in the Rapid Screening of Endocrine Disrupting Chemicals KANG Yike, RU Shaoguo, WANG Wei College of Marine Life Sciences, Ocean University of China, Qingdao 266003, Shandong Province, China Abstract Endocrine Disrupting Chemicals (EDCs) are exogenous substances that act like hormones in the endocrine system and disrupt the physiologic functions of endogenous hormones. They are sometimes also referred to as endocrine disruptors, or hormonally active agents. EDCs encompass a variety of chemical classes, including hormones, plant constituents, pesticides, compounds used in the plastics industry and in consumer products, and other industrial by-products and pollutants. With the industrial development, more and more EDCs are pervaded and widely dispersed in the environment, and the exposure to EDCs poses ever greater threat. Therefore, it becomes a top priority to reduce or avoid the increasing exposure of organisms or even human beings to EDCs. In the research field of environmental sciences, the establishment of a most convenient, efficient and effective screening method to detect chemicals with the potential to interfere with the endocrine hormone levels from pollutants is a hot project. This paper reviews the recent progress on rapid methods for detecting EDCs in the environment, and these mature rapid screenin