5_溴水杨醛氨基酸Schiff碱及其铜_配合物的制备和抑菌性能研究.pdfVIP

, Journal ofAnhuiAgr.i Sci. 2010, 38(6): 2795- 2797 52 Schiff( II) , , , , , (大连民族学院生命科学学院, 生物技术与资源利用国家民委- 教育部重点实验室, 辽宁大连 116600) [] Sch iff, 、 [] 5 52 Schiff , ( II) 、, [] , 52Br2SalAA Sch iff,( II), C- OC= N ( II); Sa2lAA Schiff, 52Br2Sa2lAA SchiffE 、B、R, , 2 , 5 52Br2Sa2lGly 52Br2Sa2lAla 52Br2Sa2lM et 52Br2Sal2Glu 52Br2Sa2lTyr, 52Br2Sal2Gly 52Br2Sa2lAA( II) , []R , R , ( II) 52; Schiff; O 625. 43 A 0517- 6611(2010) 06- 02795- 03 Research on the Preparation and AntibacterialActivity of 52Bromosalicylaldim ineAm inoAcid SchiffA lkali and ItsCopper ( I I ) Compound Z ANG Li2ying et al (KeyLaboratory ofBiotechnology Bio2ResourcesU tilization, StateE thnicAffairsComm ission andM inistry ofEdu2 cation, Dalian NationalitiesUniversity, Dalian, Liaoning 116600) Abstract [Objective] The reference for them edicine preparation ofant2i cancer and ant2ibacteriawasprovided through the study on the fac2 tors affecting the antibacterial activity ofSchiff alkali. [M ethod] Five types of52Brom osalicylaldmi ine am ino acid(Glu、Met、Tyr、Gly andAla) Sch iff alkaliswere produced and their complexesw ith copper( II) were synthesized, wh ich were expermi ented and characterized in antibacter2i al activitywith infra2red spectrum and ultraviolet spectra. [ Results] The expermi ental result indicated that Schiff alkali comp lex could be form ed through the complete reaction between 52Br2Sal andAA, when which was combinedwit the copper( II) for the form ation of the com2 p lex, the oxygen atom in C- O and nitrogen atom in C= N were pairedwith the copper( II). Comparedwith Sal2AA Schiff alkal,i band E , 2 band B and band R in 52Br2Sa2lAA Sch if