先天性胆总管扩张术后中远期并发症对患儿体格生长发育的影响.docVIP

先天性胆总管扩张术后中远期并发症对患儿体格生长发育的影响 　　作者：张志崇，苏诚，李作青，潘翠玲，莫家聪 作者单位：中山大学附属第一医院小儿外科， 广东 广州 510080 　　【摘要】 考察先天性胆总管扩张术后中远期并发症对患儿生长发育的影响。【方法】 对手术治疗2月后出现吻合口狭窄、胆道炎症等中远期并发症的CBD患儿(A组，n = 45)进行定期随访1年，每2月记录体质量、身高，同时以CBD手术后未出现并发症的患儿(B组，n = 62)和就诊的正常儿童的实测值进行对比分析，评价CBD术后中远期并发症对患儿生发发育的影响。【结果】 A组和B组术前体质量、身高无差异(P 0.05)，但手术2月后，B组身高和体质量等指标增加快于A组，到12月时两组间体质量、身高差别具有统计学意义(P 0.05)。而且A和B两组的生长发育均滞后于正常儿童组。 【结论】 CBD并发症对患儿生长发育具有显著影响，对于CBD术后并发症应积极查因、尽早处理。 　　【关键词】 先天性胆总管囊肿; 手术并发症; 生长发育 　　Impact of Postoperative Complications on Growth and Development ofChildren Suffered from Congenital Biliary Dilatation (CBD)　ZHANG Zhi-chong， SU Cheng， LI Zuo-qing， PAN Cui-ling， MO Jia-cong　Department of Pediatric Surgery， The First Affiliated Hospital， Sun Yat-sen University， Guangzhou 510080， China　Abstract： 【objective】 To investigate the impact of postoperative complications on growth and development of children suffered from congenital biliary dilatation (CBD). 【Methods】 Forty-five children (arm A) suffered from postoperative complications because of CBD were followed up once every 2 months in 1 year， and childrens weight， body height， were measured. Sxity-five children (arm B) undergone operative but not suffered from postoperative complications and 45 normal children were as CBD control group and normal control respectively. 【Results】 The difference of weight， body height were not significant (P 0.05) between arm A and arm B when the operation were performed， while the 2 indexes of arm A were increased more than arm B significantly (P 0.05). The 2 indexes of both arm A and arm B were slower than normal control group. 【Conclusions】 postoperative complications because of CBD impact severely on childrens growth and development. 　　Key words： postoperative complications; children?蒺s growth and development; congenital biliary dilatation 　　先天性胆总管扩张(congenital biliary dilatation， CBD)又名胆总管囊肿(congenital choledochal cysts， CCC)是小儿外科最常见的肝胆疾病之一，对于未做手术治疗的病例其继发癌变和胆汁性肝硬化的比例可高达15.6%和41%以上，因此，手术治疗是治愈CBD的惟一