糖皮质激素对肾病综合征患儿骨代谢的影响.pdfVIP

第 21 卷第 8 期 2006 年 4 月　J Appl Clin Pediatr , Vol . 21 No . 8 Apr . 2006 4·75 · ·论著· 糖皮质激素对肾病综合征患儿骨代谢的影响 1a 2 1a 1a 1a 1b 卢立肖 ,张 　宇 ,庄捷秋 ,杨 　青 ,林瑞霞 ,张 　颖 (温州医学院附属育英儿童医院 1a. 肾内科;1b. 保健科 ;2. 温州市第二人民医院 儿科 ,浙江 温州 325027) Influence of Glucocorticoid on Bone Metabolism in Children with Nephrotic Syndrome 1a 2 1a 1a 1a 1b LU Li - xiao , ZHANG Yu , ZHUANG Jie - qiu , YANG Qing , LIN Rui - xia , ZHANG Ying ( 1a. Department of Nephrology ;1b. Department of Health ,the Yuying Children′s Hospital Affiliated to Wenzhou Medical College ; 2. Department of Pediatrics ,the Second People ′s Hospital of Wenzhou ,Wenzhou 325027 ,China) ( ) ( ) Abstract : Objective 　To study the influence of glucocorticoid GC treatment on bone metabolism in children with nephrotic syndrome NS . Methods 　Forty - eight children with idiopathic nephrotic syndrome ( INS) were assigned as study group treated with GC and caltrate. Serum levels ( ) ( ) ( ) ( ) of osteocalcin BGP ,bone - specific alkaline phosphatase BALP , parathyroid hormone PTH and cal