聚_DL_乳酸可吸收膜在手术后膝关节粘连性僵直治疗中的应用.pdfVIP

CRTER 中国组织工程研究与临床康复 第11卷第26期 2007-07-01出版 聚-DL - 乳酸可吸收膜在手术后膝关节粘连性僵直治疗中的应用 宋 飒，苏 琰，眭述平，张先龙，曾炳芳(上海交通大学附属第六人民医院骨科，上海市 200233) 者 Treatmentofkneejointadhesivestiffnessafteroperationwith53例，男32例，女21例；年龄 18～51岁。按完全随机化方 poly-DL-lactideresorbablefilm 法将53例分成两组，实验组28例，对照组25例，两组性别、 SongSa, SuYan, SuiShu-ping, ZhangXian-long, ZengBing-fang 年龄、病情等比较差异无显著性意义，有可比性。所有患者术前 (DepartmentofOrthopaedics,SixthPeoplesHospital,ShanghaiJiao TongUniversity,Shanghai 200233,China) 均签署了知情同意书，并且本实验方案得到了院伦理委员会的 批准。 Abstract 设计、实施、评估者：均为本文作者，实验过程未采用盲法评估。 FromJune2004toOctober2006, 53casesofkneejointadhesive stiffness afteroperation in DepartmentofOrthopaedics, the Sixth 干预措施： Affiliated Peoples HospitalofShanghaiJiao Tong Universitywere 手术方法：本组病例手术的主刀医师为固定的2名医师完 randomlydividedintotwogroups. Inexperimentalgroup, 28cases were treated with adhesiolysis and poly-DL-lactide (PDLLA) 成。连续硬膜外阻滞或蛛网膜下腔阻滞麻醉成功后，上气囊止血 resorbable medicalfilm. Incontrolgroup, 25 cases were treated 带。对于未行内固定取出的患者，先行内固定取出术，然后行粘 merelywithadhesiolysisandPDLLAresorbablemedicalfilmwasnot appliedafteroperation. The follow-upperiodwas equaltoorover 连松解术。通常取大腿外侧原切口，向下延长，绕过髌骨外侧缘。 2.5 months, with a mean period of5.5 months. In experimental 必要时可加作膝内侧小切口。逐层分离，探查股中间肌和髌上 °. In control group, the average flexion angle ofknee was 115.6 囊，切除粘连纤维化的髌上囊和部分股中间肌，在股四头肌深 group, the average flexionangle°. There ofkneewere was 95.8 significantdifferencesbetweent