小剂量多巴酚丁胺合用硝酸酯超声心动图识别冬眠心肌_杨跃进.pdfVIP

# 592 # C hin J Intern M ed, Sept ember 1998, Vol 37, N o 9 ## 杨跃进 田军 尤士杰 徐义枢 高润霖 武玉兰 Dobu 2 DE 2 3 , Dobu 3~ 5 Lg#kg - 1#m in- 1 24 0~ 300 Lg/ m in 2 DE , CRV , 3 2DE 16 CR V , , 122 , Dobu 2DE 671 2 % ~ 6 81 0% , CRV , 841 6 % ~ 851 7% , 83 9 % 8414 % ~ 8513% Dobu 2 DE , Dobu , Two-dimensional echocardiography with combined low- dose dobutamine and nitrate in identifying hiberna- ting myocardium Yang Yuej in, Tian Jun, You Shij ie, et al. Cardiovascular Institute and Fuwai Heart Hosp ital, Peking Union edical College, ChineseAcademy of edical Sciences, Beij ing 1000 37 Abstract Objective To evaluate the accuracy and saf ety of tw o- dimensional echocardiography 2DE w ith combined low- dose dobutam ine Dobu and Isoket intravenous agent of Isosorbide dinitrate, Schw arz Pharm a AG in identifying hibernating myocardium Methods 2DE w ith combined low dose 3 and 5 Lg#kg- 1#m in- 1 Dobu and Isoket m ean of 294 8? 17 3 Lg/ min w as done in 23 patient s w ith old myocardial inf arction OM I w ho w ere scheduled to undergo coronary revascularization CRV CRV included successful, coronary angioplasty in 17 and coronary bypass surgery in 6 and the f ollow-up 2DE w as done about 3 months after CRV By using a 16- segment model and sem iquantitative analysis m ethod, the left ventricular regional w all motion and thickening in each segment w as graded and scored The hibernating myocardium segments detected w ere compared w ith the actual post- CRV functional improvement of the corresponding segm ent s to calculate the sensitivity, specificity and accuracy of the test in identifying hibernating myocardium T he safety of the test w as also assessed Results Among 122 abnorm al segm ents in the 23 patient s w ith OM I, hibernating myocardium segm ent s w ere detected by low- dose Dobu combined w ith Isoket 2 DE test in 67 2% ~ 68 0% T he sensitivity, specificity and accu