食管鳞状细胞癌术后辅助治疗研究进展.pdfVIP

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食管鳞状细胞癌术后辅助治疗研究进展.pdf

Journal of Chinese Oncology,2015,Vol.21,No.1 食管鳞状细胞癌术后辅助治疗研究进展 许亚萍综述,毛伟敏审校 (浙江省胸部肿瘤(肺、食管)诊治技术研究重点实验室,浙江省肿瘤医院,浙江杭州310022) 摘 要:手术是可切除食管癌的主要治疗手段,但单纯手术疗效较差。 CROSS 研究的发表使 新辅助放化疗成为食管癌研究的热点,并成为以腺癌为主的西方国家的标准治疗手段。 而我 国, 以上的患者为鳞状细胞癌。 近年来,术后辅助治疗在食管鳞状细胞癌中也进行了较 90% 为深入的研究。 文章主要就食管鳞状细胞癌术后辅助治疗的研究进展进行综述。 主题词:食管肿瘤;鳞状细胞癌;外科手术;辅助治疗 中图分类号: 文献标识码: 文章编号: ( ) R735.1 A 1671-170X 2015 01-0056-05 doi :10.11735/j.issn.1671-170X.2015.01.B013 The Current Status of Adjuvant Therapy for Esophageal Squa- mous Cell Carcinoma Postoperation , XU Ya-ping MAO Wei-min (Zhejiang Key Laboratory of Diagnosis Treatment Technology on Thoracic Oncology (Lung and , , , ) Esophagus) Zhejiang Cancer Hospital Hangzhou 310022 China : , Abstract Surgery is the preferred therapeutic strategy for esophageal cancer. But most of pa- tients still die of recurrence or distant metastases even in the presence of radical resection and extended lymph node dissection. Since the Chemoradiation therapy for Oesophageal cancer fol- , lowed by Surgery Study (CROSS) preoperative chemoradiation therapy is considered the standard of care in Western countries where most of esophageal cancer cases are adenocarcinoma. Howev- , er more than 90% of esophageal cancer is pathologically diagnosed as squamous cell carcinoma , in China. For several decades there have been numerous efforts on adjuvant therapy to improve

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