乳腺叶状肿瘤超声表现及病理对照分析.pdfVIP

中国医学影像技术研究会腹部超声专业委员会第一届全国腹部超声学术交流会暨肝胆超声新进展研讨会 谱信号，对照侧可见充盈管腔的血流信号及随呼吸变化的血流频谱；病理检测示实 验侧股静脉可见血栓充满管腔，且与管壁无粘连，对侧股静脉没有血栓形成。 结论 建立了兔深静脉血栓动物模型。 关键词 深静脉血栓；动物模型；兔 Modeling of Acute Deep Venous Thrombosis in Rabbits Abstract: Objective To establish a model of deep venous thrombosis (DVT) in rabbits. Methods Animal models of venous thrombosis were made by blocking venous flow with a vascular clamp temporarily, injuring the vascular wall, and injecting thrombin in the distal vein in one side of rabbits. Then fixed the hip and knee joints of the operated sides in the flection position with plaster. 48 h later, the femoral veins on both sides were examined with the ultrasonography and pathology. Results All the rabbits survived after operation. The ultrasonography showed that the femoral veins on both sides were virtually anechoic. However, the veins on the operated sides couldnt be compressed and no flow was detected, the on control side were just the reverse. The veins on the operated side was filled with thrombus which had not adhered on the wall, but no thrombosis occurred in the control side. Conclusions A model of DVT was established in rabbits. Key words: deep venous thrombosis; animal model; rabbits 乳腺叶状肿瘤的超声表现及病理对照分析 陈绮璐 汤庆 （广州医学院第一附属医院超声科，Email ） 【摘要】 目的 研究乳腺叶状肿瘤(phyllodes tumor of the breast ，PTB) 的超声声像 图特征及其病理基础，进一步提高对本病的认识。方法 回顾性分析我院经手术病 理证实的 30 例 PTB 的二维及彩色多普勒血流显像（CDFI ）超声表现，并与病理结 果对照。结果 30 例 PTB 患者中良性 18 例、交界性 7 例、恶性 5 例。二维超声图 像 PTB 表现为明显分叶或浅分叶的肿块 20 例、呈椭圆形或类圆形 10 例，具有体积 较大、内部回声不均匀而后方回声增强、良性者有包膜边界清而恶性者边界模糊不 清等特征。CDFI 表现出良性病例血流 0～ Ⅰ级，恶性病例血流Ⅱ～Ⅲ级、并且阻力 指数偏高（RI 0.75 ）。PTB 病理主要为大量间质异形细胞成分并膨胀性生长、变性 坏死及恶性者包膜侵犯等，此病理基础与上述声像图特征相对应。结论 超声对 PTB 的术前诊断、鉴别诊断和术后随访具有重要的临床价值，尤其CDFI 显示肿瘤的血供 情况能为临床提供重要的诊断依据。1 【关键词】 乳腺 叶状肿瘤 超声检查 病理对照 作者简介：陈绮璐（1984.3 — ），女，医学学士，住院医师 研究方向：超声诊断学