Blood gas analysis and acid-basic disorder.ppt

Blood gas analysis and acid-basic disorder Blood Gas Analysis Arterial blood Sea level (101.3kPa, 760mmHg) Quiet Anti-coagulate blood Inspire air (Whether O2 supply) Clinical Significance To evaluate respiratory failure type Ⅰ or type Ⅱ To evaluate acid-basic disorder How to evaluate respiratory failure? PaO2: Arterial blood oxygenic partial pressure. Normal: 95-100mmHg (12.6-13.3kPa) Estimate formula of age: PaO2=100mmHg-(age×0.33) ±5mmHg Hypoxia Mild: 80-60mmHg Mediate: 60-40mmHg Severe: 40mmHg Respiratory Failure PaO260mmHg respiratory failure Notice: sea level, quiet, inspire air rule off other causes ( heart disease) Classification of Respiratory Failure PaCO2: The carbon dioxide partial pressure of arterial blood Normal: 35-45mmHg (4.7-6.0kPa) mean: 40mmHg Classification of Respiratory Failure Type Ⅰ TypeⅡ PaO2 (mmHg) 60 60 PaCO2 (mmHg) ≤50 50 Other Parameters SaO2: Saturation of arterial blood oxygen Normal: 0.95-0.98 Significance: a parameter to evaluate hypoxia, but not sensitive ODC ( Dissociation curve of oxygenated hemoglobin): “S” shape PA-aO2: Difference of alveoli-arterial blood oxygenic partial pressure. Normal: 15-20mmHg (30mmHg in the old) Significance: a sensitive parameter in gas exchange PvO2: Oxygenic partial pressure of mixed venous blood. Normal: 35-45mmHg mean: 40mmHg Significance: Pa-vO2 is to reflect the tissue absorbing oxygen. CaO2: The content of the oxygen of the arterial blood. Normal: 19-21mmol/L Significance: a comprehensive parameter to evaluate arterial oxygen. Parameters in acid-basic disorder evaluation PH: negative logarithm of Hydrogen ion concentration. Normal: 7.35-7.45 mean: 7.4 HCO3- (bicarbonate): SB (standard bicarbonate) AB (actual bicarbonate) SB: the contents of HCO3- of serum of art