分子时代的白僵菌研究.pdfVIP

Mycosystema 菌 物 学 报 15 November 2011, 30(6): 823-835 jwxt@ ISSN1672-6472 CN11-5180Q ©2011 Institute of Microbiology, CAS, all rights reserved. 分子时代的白僵菌研究 1,2* 2 2 2 2 李增智 黄勃 陈名君 王滨 樊美珍 1 泛亚生命研究院 上海 200433 2 安徽农业大学微生物防治省重点实验室 合肥 230036 摘 要：白僵菌属是全球分布的最常见的虫生真菌。自上世纪90 年代以来，有关白僵菌的研究进入分子时代，各方面的研 究都有快速甚至是突破性的进展。作为复合种的球孢白僵菌和布氏白僵菌已被分割，而且还有其他新种被陆续命名，有多种 有性型被发现；在查明一些致病基因及其作用机制后，通过转基因改良菌株工作取得突破性进展；分子生态学的研究解决了 与白僵菌在农林生态系中的流行有关的一些难题。文中就白僵菌的分类学与系统演化、生物学、分子致病机制与基因工程， 以及生态学与流行病学等方面的研究进展进行了综述。 关键词：白僵菌，分子系统学，线粒体DNA ，分子致病机制，基因工程，分子生态学，流行病学 Studies on the genus Beauveria in molecular era LI Zeng-Zhi1, 2* HUANG Bo2 CHEN Ming-Jun2 WANG Bin2 FAN Mei-Zhen2 1BioAsia Life Science Academy, Shanghai 200433, China 2Provincial Key Laboratory of Microbial Control, Anhui Agricultural University, Hefei 230036, China Abstract: Beauveria spp. are the most common cosmopolitan entomogenous fungi. All aspects of the studies on Beauveria have been achieving rapidly and substantially since the research of entomogenous fungi entered a molecular era in the early 1990’s. Beauveria bassiana and B . brongniartii as species complex were divided and segregated into several new species as some teleomorphs discovered. Based on the revealed pathogenic genes and their function mechanism, strain improvement obtained breakthroughs by gene transformation. Tough problems related to prevalence of B . bassiana in different crop and forest ecosystems have been solved through molecular ecological approaches. In the present paper, taxonomy, phylogenetics, biology and molecular pathogenesis, as well as ecology and epizootiology of Beauveria spp. are reviewed. Key words: Beauveria, molecular systematics, mtDNA, molecular pathogenesis, gene