埃兹蛋白及CD44v6参和卵巢癌侵袭转移的机制.pdfVIP

·2124· 埃兹蛋白及CD44v6参与卵巢癌侵袭转移的机制 胡雪梅 郭钰珍 兰州大学第二医院妇产科(甘肃兰州) 730000 中国图书分类号盯2r7．弱 文献标识码A 文章编号1001-4411{7mOSJ 15-2124-03 【摘要】 侵袭，Egrin有望成为肿瘤早期转移的重要指标之一。 Ezrin 【关键词】 CD44v6卵巢癌免疫组化 in oninvasionandmetastasismechanismofEzrinandCIM4v6 ovar- Study epithelial Jan neoplasm HU Obstetricsand of Xue—Mei，GUOYu—Zhen．Departmentof Gynecology，theSecond筋玩蒯ClinicalHospital Lanzhou 730000。China University．GanSu Abstract themechanismofinvasionandmetastasisofezrlnandCD44v6in ovarian Objective：Tostudy epithelial detectedimmunohlstochemicalmethodin ovarian ofezrinandCD44v6W88 neoplasm．Methods：Theexpression by epithelial andnormal cellsofEgrinandCD44v6 specimens)，ovarianbenign(12specimens)tumorovarian(12specimens)．1bllI缸：Positive of CD44v6Wallcell andmembranein wel℃dark Ezrinand staining brown，thepositiveexpression cytoplasm Ezi{n ovarianhaddownward intheorderof showed inthe normal， that：(DThe levels(100％，91．7％，54．3％)of tendency expression astatistic ofovari- benign，ovarianepithelialneoplasms(P0．05)，thereW88correlationintumorgrades，clinical8ta秽，pathologytypes an in had intheorder0f