T2mapping序列对强直性脊柱炎的早期诊断价值.pdfVIP

· 344 · 浙江临床医学2015年3Y]第l7卷第3期 T2mapping序列对强直性脊柱炎的早期诊断价值 甄涛 胡大成 陈文辉★ 【摘要】 目的 探讨T2mapping序列对强直性脊柱炎 (As)的早期诊断价值。方法 收集有慢性炎性下腰痛症状的患者50例，其中临床 诊断NAS~364f,]，另14q,]诊断为单纯慢性下腰痛 (LBP)。所有患者均进行骶髂关节常规序列及8回波T2mapping序列的扫描，分别测量两 组患者双侧骶髂骨骨性关节面下骨髓的T2值，并进行统计学分析。结果 As组左、右侧及双侧骶骨T2值与LBP组比较差异无统计学意义。As 组左、右侧及双侧髂骨T2值均大于LBPS~-(P0．05)，差异有统计学意义。36例AS患者中的26~,i中共发现60处病灶，病灶与其周围相对正常 组织比较，差异有显著性 (P=-0．000)。结论 T2mapping序列可早期发现骶髂关节骨髓T2值的改变，可对As早期骨髓病变与单纯的慢性下 腰痛患者进行鉴别。有利于患者的早期诊断。 【关键词】 T2mapping 磁共振 骶髂关节 强直性脊柱炎 【Abstract】 ObjeetiveToinvestigatethevalueofT2mappingsequenceinearlydiagnosisofankylosingspondylitis．Methods50patientswith chronicinflamatorylow backpainsymptomswerecollectedinthisstudy，outofwhich36patientswereclinicallydiagnosedasASandtheremaining 14assimplechroniclowbackpain (LBP)．Imageswereobtainedusinga1．5TMRscannerHDxtGE．Thesequencesincludedtraditionalsequences and8echoT2mappingsequence．T2valuesofsubchondralbonemorrow inbilateraliliumnadsacrumalongthesacroiliacjointweremeasuredusing GEAW4．4post-processingworkstation．Anindependenttwosamplet-test (SPSSVersion18)wasusedtostatisticallynaalysethedifferenceofT2 valuesbetweenASna dLBPpatientswithPvalueofO．05asthelevelofstatisticallysing ificnatdifferent．Results Therewasnostatisticallysing ificant differencebewteentheASna dLBPgroupofthemena T2valuesinbilateralsacrum．Themena T2valuesinbilateraliliacbonemarrow o·fASpatients werehigherthantheLBPpatients (P0．05)．Therewere26patientswithatotalof60lesionsin36ASpatients．Themena T2valuesofthelesions werehigherthantheneighboringrelativelynormaltissues．(P0．05)．Conclusion T2mappingsequencecoulddetecttheearlychnageoftheT2values of bonemarrow ，bywhichearlybonemarrow lesionsofnakylosingspondylitiscouldbedetectedna dwecouldnsethistechnologytodifferentiate simplechroniclow backpainnadASpatients． 【Keywords】 T2mapping Magneticresonance SacroiliacjointAnkylosingspondylitis 血清学检测 阴性脊柱关节病 (SpA