儿童髓母细胞瘤术后放疗_化疗的治疗进展.pdfVIP

26 11 2011 6 J App l Clin P ediatr, Vo .l 26No. 11, Jun. 2011 # 884# # # DOI: 10. 3969/j. issn. 1003- 515X. 2011. 11. 027 儿童髓母细胞瘤术后放疗化疗的治疗进展 纪文元,梁 平 (重庆医科大学附属儿童医院神经外科, 重庆 400014) : (M B), 17. 7%, 3M B 25% ~ 30% M B , , M B, , , , , 2011, 26( 11): 884- 886 : 髓母细胞瘤; 治疗; 儿童 : R729 : A : 1003- 515X( 2011) 11- 0884- 03 Advances in Treat entofMedulloblasto as inChildren JI Wen - yuan, LIAN GP ing ( D epartment f N eur surgery, Ch ildrencsH sp ital f Ch ngqing M edicalU niversity, Ch ngqing 400014, China) Abstract: M edull blast ma(M B) ccursm stly in children. This acc unts f r 17. 7% f prmi ary central nerv us system tum rs in chil- dren. These children less than 3 years ld acc unts f r 25% - 30% f children w ith MB. M B has higherm alignant degree, n t cmp letely re- m ved w ith surgery d ne easily, and it ism re sensitive t radi therapy and chem therapy. Current treatment strategy f rM B patients is surger- y f ll wed by radiati n and chem therapy. V ari us regmi ens f p st perative radi therapy and chem therapy have been investigated recently in rder t mi pr ve the utc m es and av idits side effect. In this article, the recent advances in the treatment fM B w ere rev iewed. JApplClinPediatr, 2011, 26( 11): 884- 886 Key words: m edull blast m a; treatmen;t child (MB ) Bailey 1925, MB, 3 4 a , : 80% 60% ( 48% , , WHO 76% ) ; 3 5 a: (M 0 Ô 75% MB 64% ~ 82% 65% ~ 85% 10 582MB 30% ~ 40% ), 30% ~ 45% [ 2] MB [ 1] 17. 7% , 6~ 11 MB 40% 3MB 25% ~ 30%