膜分离技术与传统工艺对六味地黄活性多糖富集效果的比较.pdfVIP

386 Journa l ofPharm aceutica l P ractice Vol. 25 2007 N o. 6 钟 蕾, 赵汉臣, 闫 荟, 王 瑞, 王苏会(, 100700) : 比较分析膜分离技术与传统工艺对六味地黄多糖 性成分的富集效果: 采用纳滤膜和 10 万分子量的超滤膜对两种工艺制得的六味地黄方药液进行分段富集, 建立硫酸 蒽酮法测定各分段溶液 的含糖量: 采用膜分离技术制成的滴心丸中 性多糖含量为经传统工艺制得的胶囊的 615倍: 在富集六味地黄 性多糖方面, 膜过滤工艺较传统工艺具有较大的优势 六味地黄 性多糖; 膜分离技术 : R 944 : A : 1006 0111( 2007) 06 0386 03 E ffect an a ly sis of th e con cen tra t ion of L iuw ei D ihu an g p olysacch ar ides by th e m em br an e sepa ra t ion techn iqu e and th e tr ad it ion a lm eth od ZHONG Le i, ZHAO H an2chen, YAN Hu i, WANG R ui, WANG Su2hui(Dept1 of Pharm acy, GeneralH osp ita l ofBe ijingM ilitary R e2 gion, Be ij ing100700, Ch ina) AB STR AC T O b ectiv e: To com pare the effect b etween the m em brane separation techn ique and the traditiona lm ethod be ing u sed to concentrate polysaccharides from L iuwe i D ihuang formu la1 M eth ods: The extract liqu id of Liuwe i D ihuang form ula was divided into severa l leve ls and segments u sing nanofiltration and u ltrafiltration of 10 000M r1 The polysacchar ides in every level. s extracted liquid w ere quantitate by su lfuric ac id2anthrone color mi etr icm ethod at detecting wave length 625 nm 1 R esu lt s: The polysaccharides in the pro2 duction m ade by m em brane separation techn ique w ere 61 5 tmi es as much as that in the production m ade by the traditional m ethod1 C on c lu sion: The m embrane sep aration techn ique was sup er ior in concentration polysacchar ides com p ared w ith the trad itiona lm ethod1 K EY W OR D S polysacchar ides in L iuw e i Dihuang formu la; m em brane sep aration technique 5# , 6, 1 , , , , / 111 仪器 TU 1201 ( 0 ); FZ( , ); PS ( 12 mm,