氢质子磁共振波谱_1H_MRS_技术应用.pdfVIP

医学影像学杂志2007 年第 17 卷第 8 期　J Med Imaging Vol. 17 No. 8 2007 ·综 　　述· (1 ) 氢质子磁共振波谱 HMRS 技术应用 1 2 邝 　菲 　综述 ,王 　飞 审校 ( 1. 南京军区鼓浪屿疗养院影像科　福建　厦门　361002 ;2. 上海市第二军医大学长海医院放射科　上海　200433) ( ) 　　【摘 　要】　在过去的 10 年里磁共振波谱 MRS 技术及软件逐渐的发展并完善起来 ,它所带来的大量生化信息可以对脑 部病变做出更精确的阐释。每种形式的波谱都是体内实际生化演变的一个窗口 ,波谱数据的分析应该建立在与病理相 联系的生化过程的相关知识的了解上 ,因此深入的了解基本代谢产物能帮助我们更加准确的分析脑部病变。本文主要 阐述了MRS 的基本技术 ,脑部几种主要代谢产物的产生机制及其意义。 (1 ) 【关键词】　氢质子磁共振 HMRS ;代谢产物 ;诊断 ;病理 ( ) 中图分类号:R445. 2 ;R811 　　　文献标识码 :A 　　　文章编号 :1006 - 9011 2007 08 - 0871 - 04 1 The application of HMRS technique KUANG Fei , WANG Fei 1. Department of Radiology , Gulangyu Convalescent Hospital , Xiamen , Fujian 361002 , P. R . China 2. Department of Radiology , Changhai Hospital , Second Military Medical University , Shanghai 200433 , P. R . China 【Abstract 】　With the development of technique and software in the past 10 years , H proton magnetic spectroscopy (1HMRS) has been used to glean enormous amount of information about the metabolic status of the brain lesions for accurate interpretation. Each spectrum is a window on the actual biochemical changes taking place within the living tissues , Interppretation of MRS data , therfore , must be based on general knowkedge of biochemical processes in association with pathological changes. So continous expansion of knowledge can help us more accurate analysis brain lesions. We mainly review the technique of MRS , the forming mechanism and significance of main metabo lites of brain. 1 【Key words】　HMRS; Metabolite ; Diagnosis ; Pathology 　　神经影像学是临床诊断脑部病变及评价治疗后反应的