MDM2mRNA 过度表达与儿童急性淋巴细胞白血病免疫分型、FAB 分型及高白细胞的关系.pdfVIP

堑压些登盘查!!塑至墨!!鲞蔓!塑 ·331· ·论著· MDM2mRNA过度表达与儿童急性淋巴 细胞白血病免疫分型、FAB分型及高白细胞的关系。 山东省立医院儿科(250021)蒋莎义 陈力军 高 飞 刘廷亮李桂梅尹洪臣 摘要 细胞性相关。 MDM2 关t调 急性淋巴细胞白血病 免疫分型 FAB分型 高白细胞 MDM2 d螂1n蛆t●on蚰d RehHo眦Mp“on∞酗neover—exp忡ssl仰w量岫ImmuⅡophenotype，FABhjghJeu0触yte c¨dr蚰喇恤扯ute leukemla Iy唧hM鼬ljc ，Ⅲ”g H删gf^棚．皿坤一舢f盯P以函fw5·S^d”d。”g尸r鲫inc如fH。驴““，，?d月250021 order the the le她lof with AhtHctIn to relationshipof expression MDM2 study oncogene in withacute in— chssificat．onand countchiIdren in highleucocyte Iymphoblastic dividual wasassessedRT—PCR in32childrenwithALL．Thesecaseswere di— periphenllencoc”e usi“g technique several T—ALLand asweUas vided抽to L2 sub—groupsincluding non—T—A11．L】and hyperleucocytic no be ALL(NHALL)．Asa differenceiⅡthekvelMDM2 could perleucoc”ic result，8lthoughsignmcant expres3ion betweenT—ALLandnon—T—ALL wellas andL2 sub—groups(P—O．7345)asLl ssionwas seeninHALLas tothatofNHALL(P—O．0099)．Thesethat dramaticaUy compared nndings s“ggested MDM2 be associatedwith count(HALL)，butnotwiththe closeIy leucocyte ov