63例肾盂输尿管癌患者的临床病理特点并文献复习（英文）.pdfVIP

Chinese-German Journal of Clinical Oncology February 2010, Vol. 9, No. 2, P79–P85 DOI 10.1007/s10330-009-0161-0 Carcinomas of the renal pelvis and ureter: a clinicopathological study of 63 cases with a review of literature Xiuli Zhang, Shen Lv Department of Radiology, The Second Affiliated Hospital, Dalian Medical University, Dalian 116027, China Received: 24 September 2009 / Revised: 20 December 2009 / Accepted: 25 January 2010 Abstract Objective: The aim of this study was to summarize the clinicopathological characteristics of patients with renal pelvis and ureteral carcinomas, and analyze the recurrence in the remaining urinary tract and metastasis outside the urinary tract after surgical treatment. Methods: The patients’ characteristics, tumor stage and grade, recurrence and metastasis distribution were summarized by tables, respectively. Spearman rank test, Log-rank test, Kaplan-Meier survival curve, and Cox proportional hazards regression model were used to make statistical analysis. Results: A total of 63 patients with 30 men, 33 women, 30 renal pelvic tumors and 33 ureteral tumors was found. Seven had multifocal lesions. Fifty-four underwent surgical operation, which contained 49 cases of pathologically confirmed transitional cell carcinoma, 4 transitional cell carci- noma with squamous differentiation, and 1 squamous cell carcinoma. Tumor stage and grade had positive correlation. Among the 34 followed-up cases, 21 had no metastasis, 10 had metastasis, in which stage T3–4 groups accounted for 90%, and 5 developed tumor recurrences. The metastasis-free survivals had no significant difference between renal pelvic carcinoma and ureteral carcinoma, but had significant difference between high, middle and low s