《Arabidopsis RING Peroxins are E3 Ubiquitin Ligases that Interact with Two Homologous Ubiquitin Receptor Proteins》.pdfVIP

JoumaIof PIant 201 08．120 Integ阳tiVeBiology3，55(1)：1 A^lCle ReSeareh GPerOxinSareE3 UbiquitinLigaSes thatInteraCtwithTwO Ubiquitin HOmOIOgOuS PrOteinS回 Navneet Xie2and Hul’ Zha02，Qi Kaurl，Qingzhen Jianping 1 MSU-DOEPIantResearch Slate University，East 48824，USA Laboralory，Michigan Lansing。Michigan 2InstituteofGeneticsand Chinese of 100101，China DeveIopmentaIBioIogy，theAcademySciences，BeUlng authOr +COrrespOnding 7 7 Tel：+1514324620：Fax：+1513539168：E-mail：huii@msu．edu u]／、rticIescanbevjewedOn¨newi廿10utasubsc—Dtion． ．fWa¨abIeonIineon29November2012at、^^vw．iipb．netandv^^，＼^，．w¨eyon¨ne¨brary．com门oumal门ipb doi：10．1111，iipb．12014 AbstraCt Pemxisomesa陀essentiaI thatmediatevariousmetabOlic eukaWotico啊ane¨es Ona of factOrsca¨ed Ofwhichare impondependsgrOupperoxisomebiogenesis peroxins，many evOIutiOna PEXl2arethree r_Iyconsen，ed．PEX2，PEXl0，and integraI memb阳ne cruciaIfor pemxins pmteinimport．Inyeast(sacc，，aromycesce旭y括ael，RINGpemxins actas the Ofthe PEX5 E3¨gases。fac¨itatingrecyc¨ng perOxisOmeimpOrtreceptOrprOteinthrOugh areessentialtO elucidatethemOdeOfactiOnOf ubiqui稍natiOn．InpIants，RINGperOxins pIantvita¨ty．TO the