复方乳酸钠山梨醇对手术患者血电解质及血糖的影响.docVIP

复方乳酸钠山梨醇对手术患者血电解质及血糖的影响 复方乳酸钠山梨醇对手术患者血电解质及血糖的影响中国新药杂志 2000年第4期第9卷 新药与临床作者：王臻　唐思聪　汤睿单位：上海第二医科大学附属第九人民医院普外科， 上海 200011关键词：复方乳酸钠山梨醇；血电解质；血糖；糖尿病　　摘要　目的：观察复方乳酸钠山梨醇注射液对外科手术患者的血电解质及血糖的影响。方法：随机选30例手术患者，其中15例血糖正常为第1组，15例血 糖高于正常为第2组。两组患者于术后d1均输入复方乳酸钠山梨醇1 000ml，d2输 入5%葡萄糖盐水1 000ml（第1组）或5%葡萄糖盐水1 000ml加正规胰岛素10～12u(1∶4～1 ∶5 )（第2组）,在输液前后抽血查血电解质及血糖和胰岛素的值。结果：第1组患者输入两种液体后血糖均升高，两者升高程度比较无明显差异（P＞0.05）； 血电解质较输液前无明显变化。第2组患者输入两种液体后血糖和胰岛素升高程度比较有明 显差异（P＜0.01）。结论：复方乳酸钠山梨醇是细胞外液良好 替代剂，可作为手术患者特别是葡萄 糖利用障碍（糖尿病）患者的供能物质，其效果较传统的葡萄糖加胰岛素更好。 THE EFFECT OF COMPOUND INTRAVENOUS INFUSION OF SODIUM LACTATE AND　　SORBITOL ON BLOOD ELECTROLYTE AND GLUCOSE IN SURGICAL PATIENTSWang Zhen　 Tang Sicong　 Tang Rui　　（Department of General Surgery, The Ninth Peoples Hospital,Shanghai Second Medical University, Shanghai 200011）　　ABSTRACT　OBJECTIVE:The effect of compound intravenous infusion of sodium lactate and sorbitol (SLS infusion) on blood electrolyte and glucose in surgical patien ts were studied. METHODS: 30 surgical patinets were enrolled into the study. 15 of them with nor mal blood glucose (BG) comoposed of group 1 and the balance of them with higher BG composed of group 2. Patients in both groups were treated with 1 000 ml SLS i n fusion at the first day after operation. In the next day, patients in group 1 we re treated with 1 000ml 5% GNS and patients in group 2 were treated with 1 000 m l 5% GNS plus 10～12u regular insulin. Blood level of electrolytes, glucose and i nsulin was measured before and afert infusions. RESULTS: Bolld gluc ose level was rose in group 1 patients after both SLS infusion and 5% GNS treat m ent but no difference (P＞0.05)in levels of BR increase and electrolytes were observed between the two agents. The levels of BG and insulin in group 2 patien ts have significant difference(P＜0.01)between pre-and post -treatment with SLS infusioin and 5% GNS plus insulin.CONCLUSION:SLS infusion is a promise substitute for extracellular fluid and can be used as a dynamophore in surgical