Partitioned Fluid–Solid Coupling for Cardiovascular Blood Flow.pdf

Annals of Biomedical Engineering, Vol. 38, No. 4, April 2010 ( 2010) pp. 1426–1441 DOI: 10.1007/s10439-009-9895-7 Partitioned Fluid–Solid Coupling for Cardiovascular Blood Flow Left-Ventricular Fluid Mechanics SEBASTIAN KRITTIAN,1,2 UWE JANOSKE,3 HERBERT OERTEL,1 and THOMAS BOHLKE¨ 4 1Institute for Fluid Mechanics, Karlsruhe Institute of Technology (KIT), Kaiserstrasse 10, 76131 Karlsruhe, Germany; 2Computing Laboratory, University of Oxford, Wolfson Building, Parks Road, Oxford OX1 3QD, UK; 3Department of Mechanical Engineering, Fluid Mechanics, University of Wuppertal, Gauss-Strasse 20, 42119 Wuppertal, Germany; and 4Institute of Engineering Mechanics, Karlsruhe Institute of Technology (KIT), Kaiserstrasse 10, 76131 Karlsruhe, Germany (Received 31 July 2009; accepted 26 December 2009; published online 8 January 2010) Associate Editor James B. Bassingthwaighte oversaw the review of this article. Abstract—We present a 3D code-coupling approach which common cause of death in the western world. Nowa- has been specialized towards cardiovascular blood flow. For days, the diagnostic discovery of cardiovascular dis- the first time, the prescribed geometry movement of the ease is a standard procedure. However, there is still cardiovascular flow model KaHMo (Karlsruhe Heart Model) has been replaced by a myocardial composite model. uncertainty about how to evaluate the interdependence Deformation is driven by fluid forces and myocardial of fluid flow and soft tissue deformation. The vast response, i.e., both its contractile and constitutive behavior. majority of classical engineering applications focus on Whereas the