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pit_and_sex_devel_a_13胚胎性别分化
Testis Determining Factor (SRY gene product) Testes develop XY Male Sertoli cells secrete anti-mullerian hormone (AMH) AMH causes leydig cells to differentiate Testosterone Development of male duct system Degeneration of Mullerian duct Vas efferentia Female Development XX Female No TDF Ovaries Develop No AMH Mullerian ducts become the oviducts, uterus, cervix and part of the vagina Testes Determining Factor No Testosterone Wolffian Ducts Regress Mullerian Duct Primary or Epithelial Sex Chords Wolffian Duct Regressing Tubules Future Ovarian Cortex Ovarian Development Mullerian Duct Regressing Epithelial Sex Chords Regressing Wolffian Duct Regressing Tubules Future Ovarian Cortex Mullerian Duct Regressing Epithelial Sex Chords Regressing Wolffian Duct Regressing Tubules Future Ovarian Cortex Primordial Follicles Secondary or Cortical Sex Chords (egg nests) Mullerian Duct Regressing Wolffian Duct Ovarian Cortex Primordial Follicles Ovarian Medulla 2nd Sex Chords in Fetal Ovary Development of the Uterus, Cervix and Vagina Mullerian Duct Fused Mullerian Duct Hymen Ovary Regressing Wolffian Duct Mullerian Duct Broad Ligament Development (transverse anterior section) Reproductive tract develops outside the peritoneum! Ovary Regressing Wolffian Duct Mullerian Duct Regressing Wolffian Duct Mullerian Duct Genital Fold (Future Broad Ligament) (Posterior Transverse Section) Testis Determining Factor (SRY gene product) Testes develop Sertoli cells secrete anti-mullerian hormone (AMH) AMH causes leydig cells to differentiate Degeneration of Mullerian duct Testosterone Development of male duct system XY Male No TDF Ovaries Develop No AMH Mullerian ducts become the oviducts, uterus, cervix and part of the vagina XX Female No Testosterone Degeneration of Wolffian duct Phenotypic Sex Testis Determining Factor (SRY gene product) Testes develop Sertoli cells secrete anti-mullerian hormone (AMH) AMH causes leydig cells to differentiate Degeneration of Mullerian Duct Testosteron
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