Quantitative determination of uric acid using CdTe nanoparticles as fluorescence probes》.pdf

Biosensors and Bioelectronics 77 (2016) 359–365 Contents lists available at ScienceDirect Biosensors and Bioelectronics journal homepage: /locate/bios Quantitative determination of uric acid using CdTe nanoparticles as fluorescence probes Dongri Jin a, Min-Ho Seo b, Bui The Huy b,c,n, Quoc-Thai Pham b, Maxwell L. Conte b, Daniel Thangadurai b, Yong-Ill Lee b,nn a Key Laboratory of Nature Resource of Changbai Mountain and Functional Molecular (Yanbian University), Ministry of Education, Yanji 133002, China b Anastro Laboratory, Department of Chemistry, Changwon National University, Changwon 641-773, Republic of Korea c NhaTrang Institute of Technology and Research Application, VAST, 2 Hungvuong, Nhatrang, Vietnam a r t i c l e i n f o a b s t r a c t Article history: A convenient enzymatic optical method for uric acid detection was developed based on the fluorescence Received 9 July 2015 quenching of ligand-capped CdTe nanoparticles by H2O2 which was generated from the enzymatic re- Received in revised form action of uric acid. The interactions between the CdTe nanoparticles capped with different ligands 24 September 2015 (glutathione, 3-mercaptopropionic acid, and thioglycerol) and H2O2 were investigated. The fluorescence Accepted 25 September 2015 quenching studies of GSH-capped CdTe nanoparticles demonstrated an excellent sensitivity to H O . The Available online 28 September 2015