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Amathematicalmodelforpredictingthetemperature.pdf
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A mathematical model for predicting the temperature distribution in laser-induced
hyperthermia. Experimental evaluation and applications
This article has been downloaded from IOPscience. Please scroll down to see the full text article.
1995 Phys. Med. Biol. 40 2037
(/0031-9155/40/12/003)
View the table of contents for this issue, or go to the journal homepage for more
Download details:
IP Address: 95
The article was downloaded on 15/10/2012 at 06:25
Please note that terms and conditions apply.
Phys. Med. Biol. 40 (1995) 2037-2052. Printed in the UK
A mathematical model for predicting the temperature
distribution in laser-induced hyperthermia. Experimental
evaluation and applications
C Sturesson and S Andersson-Engels
Department of Physics, Lund Institute of Technology,PO Box 118, S-27 100 Lund. Sweden
Received 9 March 1995, in finalform 3 August 1995
Abstract. A time-dependent mathematical model for the heat transfer in laser-induced
hyperthermia has been developed. The model calculares the tempmure distribution in surface-
irradiated tissues. Good agreement was found between the predictions of the model and in vitro
experimental results obtained for bovine liver irradiated with an expanded beam from a Nd:YAG
laser. Surface evaporation of warer was included in the model and experimentally verified. The
discrepancy between the measured and the calculated rise in temperature at three different depths
on the axis of symmetry of the hdiating beam was found to be less than 5% after 15 min
of irradiation. When irradiating
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