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HR Planning System Integration and Upgrading Research of
A Suzhou Institution
Graph Theory
書面報告 3
學號:946349
姓名:蘇育仁
Paper
Title: A Greedier Approach for Finding Tag SNPs
Authors: Chia-Jung Changa, Yao-Ting Huanga, and Kun-Mao Chao
Publication: Bioinformatics Advance Access published January 10, 2006
1、Problem
Single Nucleotide Polymorphism (SNP)
A genetic variation when a single nucleotide (i.e., A, C, G, or T) in the DNA sequence is altered and kept through heredity thereafter.
上述是作者在paper中對於SNP的描述,SNP是同物種中,不同個體在DNA sequence間發生差異的最主要位置,而且通常只有一個鹼基會發生,如下圖:
上圖兩個個體之間,只有一個鹼基有差異,其他的序列都是一樣的,而且在那個S
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