应用中药紫河车膜治疗硬脑膜缺损.pdfVIP

F reez e一d r ied A m n io tic M em b ra n e fo r R eP a ir o f D u ra l d efe ets S P eeia lity :Surgery of trad ition alC h in ese m ed iein e A u th o r :N ian P in g Z h an g Tu to r :P ro f.F an g L iu A b str a C t o bjeetive :TO study the Probab ility of freeze一dried arnn iotie m em brane (FD A M ) as a dural sub stitu e.M eth od s:32 gu inea P igs w ere ran dom ly div ided into 4 grouP s (8 in eaeh grouP).E aeh of the guinea P igs un derw entbilateralParietalcrna ieetom y beh ind the eoronal sutu re an d b e sid e th e m id lin e to ex P o se th e dur a . O n th e right sid e ，a P ieee o f du ra m ater w a s rem o v ed . T h e du ra l d efeet w a s eo v ered w ith a P ieee o f F D A M . T h e ex P o sed du ra o n th e leftw a s eu t an d su tu red itse lf a s eon tro l. T h e an im a ls in eaeh gro u P w ere saerifiee d at 15 ，3 0 ，6 0 an d 9 0 d ay s after oP eratio n ，resP eetiv e ly .T h e im P lant s w ere h arv e sted an d sta in ed w ith h em ato x y lin 一eo sin ，an d h isto lo g iea lly an a ly z ed . B lo o d sam P les w ere eo lleeted fro m g u in ea P ig s b efore o P eratio n an d b efore saerifiee .W h ite b lo o d ee ll cou n ts w ere m ea su red . 1切 en ty 一fou r e lin iea l P atien ts w ere eh o sen for the eXP erim eni，am o n g w h om 6 P atien ts w ere P erof rm ed th e sk u ll su rg iea l oP eration s o f reP lac in g the dura m ater w ith F D A M ，an d 18 P atienis a eeeP ted th e oP eratio n s o f reP laein g the du ra m ater w ith an o th er b io lo g ica l art ifie ia l d u ra m ater-T h e d ata w ere an a ly zed b y S P S S 16 .0 sy stem so ftw are .R e su lts :A fter o P eratio n ，th e b eh av io r o f a ll gu in ea P ig s rem a in ed eom P lete