呼和浩特地区犬性肾脏衰竭临床调查与分析.pdfVIP

摘 要 犬慢性肾脏衰竭（CRF ）以渐进性且不可逆的肾实质损失和肾功能下降为特点。 本调查收集了2011～2012年期间呼和浩特地区30例犬慢性肾脏衰竭临床病例，经病 史调查、临床症状检查获取个体资料，详细分析了犬慢性肾脏衰竭时血液和尿液相 关指标的变化，并对治疗前后指标的变化进行对比。 通过调查发现，呼和浩特地区犬慢性肾脏衰竭以杂种犬多发，发病年龄多在7～ 9岁，中老年犬发生慢性肾脏衰竭的危险性较高，多发于日粮以自制食物为主的饲喂 方式，性别差异不明显，多于春夏季节发病。对血液和尿液进行分析发现，血清中 肌酐、尿素氮、磷浓度升高，多数患犬钾离子、钠离子浓度降低，pH值略有下降。 慢性肾功能患犬血液中红细胞数量与血红蛋白浓度下降。尿比重下降，出现蛋白尿。 影像学检查发现肾脏体积变大、变小或正常，肾组织回声增强。治疗前与治疗后相 比，除尿比重外，其它各项肾功能相关指标均有改善。 调查发现前来就诊的患犬多在肾脏衰竭的3 、4 阶段，氮质血症严重，电解质以 及酸碱平衡紊乱，尿比重降低，出现蛋白尿。虽然经过治疗后患犬有明显改善，但 由于就诊时多在慢性肾脏衰竭中后期，通常预后不良。 关键词：犬；慢性肾脏衰竭；调查；分析；治疗 Clinical Investigation on Canine Chronic Renal Failure in Hohhot Abstract Chronic renal failure (CRF) is clinically characterized in canines by the development of variably progressive irreversible interregnal lesions and loss of renal functions. 30 cases of canine chronic renal failure in Hohhot area occurred during 2011-2012 were collected in this investigation, and their background informations were obtained by investigation of case history and clinical symptoms examination individually. Blood and urine interrelated indexes of chronic renal failure in canines were analyzed.The index changes after and before treatment were observed comparatively. The chronic renal failures in Hohhot attacked mainly in crossbreed canine and it’s morbidity ages mostly ranged from 7 to 9 years old. The occurrence of chronic renail failure in aged and middle aged dogs had higher risk, and which attacked mainly on dogs fed with homemade diets.There no significant differences in gender but it mostly attacked in spring and summer seasons.Decreased renal function and increased serum creatinine, usea nitrogen and phosphorus concentration in serum were detected in all canines with