nucleic acid engineering - cornell university.pptVIP

Nucleic Acid Engineering Contributors: Dr. Adolf Beyer-lein Retired Chair and Professor Emeritus Dept. of Chemistry Clemson University Dr. Wusi Maki Research Professor Center for Advanced Microelectronics and Bio-molecular Research University of Idaho Dr. Hua Helen Wang Assistant Professor Dept. o Food Science Technology The Ohio State University Dr. Dan Luo Assistant Professor Dept. of Biological and Environmental Engineering Cornell University Background and Rationale Nucleic acid engineering is a bottom-up nanotechnology approach. Nucleic acid engineering is focusing on creating novel materials by intelligent design at the nano scale. Nucleic acid engineering is a platform of technology that can be applied to a myriad of applications in the agriculture and food system. Nucleic acid engineering is an evolving new field of study. Background and Rationale Nucleic acid engineering is a multidisciplinary technology, encompassing: molecular biology, chemistry, microelectronics, polymer sciences, etc. Knowledge and technology developed from health sciences (e.g., from NIH) and plant could be borrowed and adapted to animals and other agricultural system by nucleic acid engineering (analogy: similar road signs) Nucleic acid engineering can be combined with microelectronics, chemistry, polymers and biomolecular research to yield more potential building block at the nanoscale. Examples: chemically modified nucleic acids, DNA molecule doping (DNA conductor, Dr. Alocilja, Biosystems Engineering, Michigan State Univ.), polymer-DNA hybrids, etc. Background and Rationale Nucleic acid engineering is a platform technology that can find a myriad of applications for the agriculture and food systems, examples (in no particular order): Signal amplification Bio-separation/Bio-films DNA delivery (gene therapy/vaccination/Disease prevention) Vet. Medicine Bioprobes Biosensor Nanomaterials for agriculture and food Specific opportunities in theme area Novel