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cloning and expression of special strongfstrong protein from human liver.pdf

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cloning and expression of special strongfstrong protein from human liver

PO Box 2345, Beijing 100023, China World J Gastroenterol 2007 March 28; 13(12): 1799-1804 World Journal of Gastroenterology ISSN 1007-9327 wjg@ © 2007 The WJG Press. All rights reserved. BASIC RESEARCH Cloning and expression of special F protein from human liver Shu-Ye Liu, Xin-Da Yu, Chun-Juan Song, Wei Lu, Jian-Dong Zhang, Xin-Rong Shi, Ying Duan, Ju Zhang Shu-Ye Liu, Wei Lu, Jian-Dong Zhang, Xin-Rong Shi, Ying INTRODUCTION Duan, Tianjin Third Central Hospital, Tianjin Artificial Cell Laboratory, Tianjin 300170, China F protein was first isolated from mouse liver by Fravi and Shu-Ye Liu, Xin-Da Yu, Chun-Juan Song, Ju Zhang, Nankai Lindenmann in 1968 [1]. This particular protein can be University, Biology Science Institute, Tianjin 300071, China divided into F1 and F2[2]. Liver disease is the most serious Supported by a grant from the Tianjin Science and Technology disease impairing public health. Although there are many Committee, No. 023802911 diagnostic methods to estimate the severity of injury to Correspondence to: Shu-Ye Liu, Tianjin Third Central Hospital, Tianjin 300170, China. lshye@163.com the liver, none has been demonstrated to be completely Telephone: +86-22 reliable. It is therefore necessary to develop serological Received: 2006-11-30 Accepted: 2007-02-08 test methods that can precisely predict the degree of