原创力文档a prospective evaluation of iron deficiency anemia in the gi endoscopy setting role of standard endoscopy, videocapsule endoscopy, and ct-enteroclysis：在消化道内镜检查设置标准镜的作用，缺铁性贫血的前瞻性评估视频胶囊内镜和ct小肠造影，.pdfVIP
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a prospective evaluation of iron deficiency anemia in the gi endoscopy setting role of standard endoscopy, videocapsule endoscopy, and ct-enteroclysis：在消化道内镜检查设置标准镜的作用，缺铁性贫血的前瞻性评估视频胶囊内镜和ct小肠造影，
ORIGINAL ARTICLE: Clinical Endoscopy
A prospective evaluation of iron deficiency anemia in the GI
endoscopy setting: role of standard endoscopy, videocapsule
endoscopy, and CT-enteroclysis
Angelo Milano, MD, PhD, Chrysanthi Balatsinou, MD, Antonella Filippone, MD,
Maria Pia Caldarella, MD, PhD, Francesco Laterza, MD, Domenico Lapenna, MD,
Sante Donato Pierdomenico, MD, Fabio Pace, MD, Franco Cuccurullo, MD, Matteo Neri, MD
Chieti, Italy
Background: Iron deficiency anemia (IDA) is a frequently encountered condition in clinical practice. After
conventional endoscopy, the cause of anemia remains unknown in up to 40% of patients.
Objective: To evaluate prospectively the diagnostic efficacy of a systematic endoscopic approach to IDA and to
compare the diagnostic yield of videocapsule endoscopy (VCE) and CT-enteroclysis in endoscopy-negative patients.
Design: Consecutive patients with IDA were enrolled prospectively.
Setting: Open-access endoscopy within an academic hospital.
Patients: This study involved 189 patients with IDA, including 98 women and 91 men; mean ( standard
deviation) age 68 years 16.6 years.
Intervention: Patients with IDA underwent gastroscopy and colonoscopy plus ileoscopy. Endoscopy-negative
patients were further blindly evaluated by both CT-enteroclysis and VCE.
Main Outcome Measurements: Diagnostic yield of conventional endoscopy; diagnostic yield of VCE versus
CT-enteroclysis.
Results: Endoscopy results were positive in 144 of 189 patients (76.2%). CT-enteroclysis and VCE allowed a
diagnosis in 37 of 45 endoscopy-negative patients (82.2%). Overall, VCE was superior to CT-enteroclysis (77.8%
vs 22.2%; P .001), in particular when flat lesions were found.
Limitations: Single-center study.
Conc
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