a prospective, randomised eortc intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma:一项前瞻性,随机eortc组间3期研究比较选择性保留肾单位手术和根治性切除的低期肾细胞癌的肿瘤预后.pdfVIP
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a prospective, randomised eortc intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma:一项前瞻性,随机eortc组间3期研究比较选择性保留肾单位手术和根治性切除的低期肾细胞癌的肿瘤预后
E U R O P E A N U R O L O G Y 5 9 ( 2 0 1 1 ) 5 4 3 – 5 5 2
ava ilable at
journal homepage: www.eu
Platinum Priority – Kidney Cancer
Editorial by Carlo Terrone and Alessandro Volpe on pp. 553–555 of this issue
A Prospective, Randomised EORTC Intergroup Phase 3 Study
Comparing the Oncologic Outcome of Elective Nephron-Sparing
Surgery and Radical Nephrectomy for Low-Stage Renal Cell
Carcinoma
Hendrik Van Poppel a, *, Luigi Da Pozzo b, 1, Walter Albrecht c, Vsevolod Matveev d,
e f g h i
Aldo Bono , Andrzej Borkowski , Marc Colombel , Laurence Klotz , Eila Skinner ,
Thomas Keanej , Sandrine Marreaud k, Sandra Collette k, Richard Sylvester k
a Department of Urology, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium
b Department of Urology, Instituto Scientifico H.S. Raffaele, Milano, Italy
c Department of Urology, Krankenanstalt Rudolfstiftung, Vienna, Austria
d Department of Onco-Urology, Cancer Research Centre, Moscow, Russia
e Department of Urology, Ospedale Di Circolo E Fondazione Macchi, Varese, Italy
f Department of Urology, Warsaw School of Medicine, Warsaw, Poland
g Department of Urology, Hopital Edouard Herriot, Lyon, France
h Division of Urology, Toronto-Sunnybrook Regional Cancer Centre, Toronto, ON, Canada
i Department of Urology, University of Southern California School of Medicine, Los Angeles, CA, USA
j Department of Urology, Medical University of South Carolina, Charleston, SC, USA
k EORTC Headquarters, Brussels, Belgium
Article info Abstract
Article history: Background: Nephron-sparing surgery (NSS) can safely be performed with slightly
Accepted December 10, 2010 higher complication rates th
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