腹腔镜宫颈鳞癌术并卵巢侧面移位术后卵巢内分泌功能及并发症的研究.pdfVIP

摘 要 旦且吐探讨年轻早期宫颈鳞癌患者侧面卵巢移位术 LOT 后影响卵巢内分泌功能的因素及并发症， 探讨监测卵巢内分泌功能的客观指标。 象，通过测定患者术前术后血清女性激素、抑制素B INHB 水平、B超检查及患者填写围绝经期综合 征量表，调查术后卵巢内分泌功能及并发症的情况。 巢功能正常2例，卵巢功能减退5例； 40岁患者12例，卵巢功能正常者9例，卵巢功能减退3例，两组 例发生移位卵巢转移，1例术后一个月盆腔积液，抗炎对症治疗半月后包块消失，1例术后间歇性右 侧移位卵巢部位轻微疼痛；据22例宫颈癌并LOT患者术后6个月血清抑制素B、FSH、E。值相关性分析， 随着卵巢功能的下降，抑制素、E：水平逐渐下降，而FSH逐渐上升。 结论：年轻宫颈鳞癌患者行宫颈癌手术并LOT时，术后如果不行放疗，卵巢内分泌功能保留良好；放 疗对宫颈癌手术时移位的卵巢有一定影响，并不能完全避开放射线的照射，但卵巢移位对宫颈癌手 术后患者的卵巢内分泌功能起到了很大的保护作用：手术年龄超过40岁的患者仍然可以从LOT得益； 严格掌握手术指征的LOT并非症发生率很低，而且出现并发症的患者症状轻微，无需手术治疗；血清 INHB同FSH一样，是反映卵巢储备功能的敏感指标。 关键词：宫颈鳞癌；卵巢移位；卵巢内分泌功能；并发症 AB STRACT the of theovarianfunctionandthe in women factors ．Ob—iective：．Toinvestigate influencing sequelaeyang 谢m cervical carcinomawhounderwentradical earlystage squamous andLOT 1ateralovarian the indicators the lymphadenectomy transposition ，andobjective ofmonitoring ovarianfunction． cervical cancer 19caseswho ．M．．．．．．e．．．．t．．h．．．o．．。．d．．．—s—：22younger squamouspatients surgeryage 45years including were underwentradical andLOTand3caseswhoseovarian hysterectomy,pelficlymphadenectomy retainedinsituwererecruitedtoour usedthe the study．We Kuppermanstandard 1995 toinvestigate and Inhibin climacteric ofthe and syndromepatientscombined谢饿FSH，LH，E2B INHB tojudge ovarianfunction．Andwealsousedultrasoundto the ovariestofmdoutthe of imagetransposed sequela LOT． of1 whounderwentLOThadno femalehormonelevelsand score3cases ．R．．．．．．e．．．．s．．．u．．．．．1．．t．．s．．．．：——The Kupperman differencebefore after insix levelof and operation operationmonthsp0．05 ．The scoreinLOTand are thanthatintheno higher radiotherapy postoperationradiotherapygroup group than in 7 were thatwhoseovarianwcTeretained 畔0．05 ，but higher situ畔0。05 ．Inpatients significantly who the in40—45 hadnormalovarian whose acceptedsurgery yearsold，2patients function，5patients ovarianfunctionweredeclined．In12 who the lessthen40 yearsold，9 patientsa唧tedsurgery patients all two there hadnormalovarian whoseovarianfunctionwere the function，3 declined