胃腺癌中eif5a2和ki-67的表达及其临床意义.pdf

结论： 1．EIF-5A2在胃腺癌组织中呈高表达，在肿瘤不同浸润深度、有无淋巴结转移、 达水平逐渐升高。 2．EIF．5A2表达和硒．67表达呈显著正相关。 3．ElF一5A2、Ki一67表达是胃腺癌患者预后不佳的危险因素，联合检测可作为胃 腺癌患者预后的参考指标。 关键词：EIF．5A2；胃腺癌；免疫组织化学； andClinical ofEIF5A2 inGastric Expression significance gene Adenocarcinoma Abstract Gastricadenocarcinomaisoneofthemostcommon Background has incidenceand studies tumors，and mortality．Recently malignant high of demonstratedthatthereare cytogenetic high-frequencyamplifications ofchromosome in tumors．It partly3qregionmalignantepithelial indicatesthatchromosomecontain incertainDNA 3qmay keyoncogenes newcandidate EIF一5A2wasclo