经肛门巨结肠根术后直肠感觉和顺应性的研究.pdfVIP

一、摘要 中文论著摘要·················································1 英文论著摘要·················································3 二、英文缩略语···················································5 三、论文 刖舌。’。。。‘。。’。。。’’。‘‘‘。。‘。。’‘’。’’’‘。。。。。‘‘。‘。。。。。。。。‘。。‘‘。。‘‘b前言························一·······························6 资料与方法···················································6 结果·························································8 讨论·························································9 结论·························································1l 四、本研究创新性的自我评价·······································12 五、参考文献·····················································15 六、附录 综述························································20 在学期间科研成绩············································22 致谢························································23 个人简介····················································24 ·中文结构式摘要· 经肛门 目 的 直肠感觉和顺应性是反映直肠运动功能的重要特征，如发生改变可能会影响 排便功能。本文力求对直肠感觉阈值和顺应性的检测，探讨其在评价经肛门巨结 肠根治术后患儿肛门括约肌功能中的意义。 方 法 采用高分辨多通道胃肠功能检测系统及自制的直肠感觉检测仪，对42例在 本院行经肛门巨结肠根治术后半年以上的患儿进行检测，术后随访年限平均为 22．6月(6—36月)。于检测前先行排便功能问卷调查(包括每日排便次数、控便 能力、污便及便失禁情况)，同时进行直肠功能检测。检测内容包括：静息和缩 肛时的肛管内最大压力值；肛门直肠反射；直肠感觉阈值和直肠顺应性。 继 甲 三日 禾 秘和9．5％(4／42)污便和稀便时便频。检测指标显示无症状组与正常对照组的差 异无统计学意义。检测指标显示便秘组(2／42)和污便组(4／42)，静息状态下肛 管内最大压力值分别为： (167：t：36 mmHg)和(1514-107mmHg)与对照组 (161士64mmHg)相比较便秘组高于其他三组，而污便组则明显降低，缩肛后各 组间肛管内最大压力值均明显增力l：ll直肠肛管反射恢复率为9．5％(4／42)；直肠 污便组直肠感觉阈值降低；顺应性比较(0．624-0．09 ml／ ml／mmHg)和(O．554-0．22 mmHg)，与正常对照组(1．22+0．17 ml／mmHg)相比，便秘组和污便组均有降低， (P0．05)有统计学意义。 结 论 大多数经肛门巨结肠根治术后患儿排便功能良好，肛管内最大压力值、直肠