三七皂甙联合阿匹林抗血栓治疗临床观察.pdfVIP

′ Clinical Study of Panax Notoginseng Saponins Jointing Aspirin s Anti-thrombosis Treatment Speciality:Hormonology of TCM Author:Li Xiaoming Tutor:Prof.Yan Xiaoyan Abstract Objictive:This study selected notoginseng saponins （PNS ）joint aspirin and use of aspirin alone or notoginseng saponins for the treatment of thrombosis, aims to observe its blood rheology and the end point of the effects of the event of safe and effective, and this paper discusses the effects of the event of PNS joint aspirn for the incresction of ten clinical curative effect,application of the reduction of the adverse reactions and the incidence,cardio-cerebrovascular events, expecting the proposed joint control schemes. Metehods: The 81 cases 0f clinically diagnosed as elderly patients with coron- ary heart disease (CHD) was divided into three groups randomly, including as- pirin group, 28 cases, 100mg/d PO.;PNS group of 26 cases, 200mg general o- ral panax notoginseng, tid ,PO.and Sanqi ( panax notoginseng) saponins joint aspirin 27 cases,the jointed use of aspirin 100mg/d PO,and panax notoginsen- g 200mg, tid PO. Three groups were observed for six months. Three groups w- ere observed sickness ′S change, detection prothrombin time (PT), prothrom- bin time international standardization ratio (PT - INR), D - dimers (D - D), plate- let aggregation function (PAgT), allergic c-reactive protein (CRP) and the cha- nge of EKG. And to do bolld rution ,urine routine,feces routine , feces occult bl- ood as well as liver and kidney function tests,statistical analysis to determine the efficacy and safety. Results: Clinical observation found that three groups all can