动脉硬化闭塞症症细胞因子的变化规律与中医证型的相关性研究.pdfVIP

Research on the Significance of Changes of Inflammatory cells in Traditional Chinese Medicine Syndromes of Arteriosclerosis Obliterans Specialty: Peripheral Vascular Diseases , Surgery of TCM Author: Tan Jian-feng Tutor: Prof. Hou Yu-fen Abstract Objective: To present the subject through the inflammatory cytokines levels and atherosclerosis obliterans syndrome differentiation relations research, to further explore arteriosclerosis obliterans pathogenesis. Methods: Screening of patients with arteriosclerosis obliterans in 60 cases and 30 cases of healthy control group for the study, according to TCM syndrome is divided into blood stasis and pathogenic dampness-heat type of the 30 cases, collect general information on research subjects and to detect high-sensitivity C reaction protein, tumor necrosis factor-α, IL -6, IL-10, analysis and comparison between various types and with the control group between the indicators of changes in micro-inflammation. Results: The study showed patients with ASOs pro-inflammatory cytokines as Hs-CRP, TNF-α, IL-6 were increased, compared with the control group with a very significant difference (P 0.01), which pro-inflammatory cell factor levels of pathogenic dampness-heat type are significantly higher than blood stasis (P0.05, P0.01); and IL-10 levels in the blood stasis, pathogenic dampness-heat and the control group there was no significant difference between. Conclusion: ASO syndrome types of TCM are the existence of the Hs-CRP, TNF-α and IL-6 increased the phenomenon, and in different types of c