益气活血、通络癥法治疗pfsgs气虚血瘀证的临床研究.pdfVIP

Clinical Study on Primary Focal Segmental Glomerulosclerosis (FSGS) of blood stasis due to qi deficiency with methods of tonifying qi and invigorating the circulation of blood, dredging collaterals and dissipating agglomerate Special: Internal Medicine of Integrated TCM and Western Medicine Student: Liu Yan Tutor: Prof.Guo Zhaoan Abstract Objective: To investigate the effect of yi-qi-tong-luo-yin （YQTLY ） treating pFSGS of blood stasis due to qi deficiency on the basis of western medicine treatment. To explore the advantages and feasibility of combining traditional Chinese and western medicine treating pFSGS and lay the foundation for further improvement. Methods: 60 patients with pFSGS of blood stasis due to qi deficiency were randomly divided into 2 groups, experimental group and control group, each group was 30 cases. Patients in control group were treated by routine therapy, while patients in experimental group were treated by combination of YQTLY and routine therapy. The course of treatment is 2 months. The curative effect and the related indexes were determined before and after treatment, the change of patients clinical symptoms was recorded. Results: The total effective rate in the experimental group (96.67%) was higher than that in the control group (56.66%, p0.01). It is significantly different between the scores of pro-treatment and post- treatment (p0.01) in the experimental group. There is no significant difference in the remission of pFSGS between the control group and the experimental group. There were significant difference between two groups on 24h urine protein, ALB, TCH and TG after treatment (p0.01). There were significant difference between before and after treatme