肥大细胞对THP-1巨噬细胞源性泡沫细胞胆固醇分配和流出的影响PPT课件.pptVIP

肥大细胞对THP-1巨噬细胞源性泡沫细胞胆固醇分配和流出的影响 促动脉粥样硬化(As)形成 MCs加速oxLDL诱导平滑肌细胞泡沫化。 Compound48/80处理的新西兰白兔和apoE-/-鼠主动脉脂纹形成比对照组早，面积大，分布广。 HDL Metabolism and Reverse Cholesterol Transport Formation of THP-1 macrophage-derived foam cells The effect of MCs on the accumulation of cell cholesterol in THP-1 macrophage-derived foam cells The effect of MCs on the distribution of cell free and esterified cholesterol in THP-1 macrophage-derived foam cells The effect of MCs on cholesterol efflux from THP-1 macrophage-derived foam cells mediated by HDL3 MCs能降解HDL3的apoA-Ⅰ； MCs能抑制HDL3介导的 THP-1巨噬细胞源性泡沫细